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Neuropilin-1 Antibody (130603) [Alexa Fluor® 488]

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Product Details

Summary
Reactivity RtSpecies Glossary
Applications Flow, B/N, CyTOF-ready
Clone
130603
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB566U-100UG
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Alexa Fluor 532
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Alexa Fluor 594
FAB566T-100UG
Alexa Fluor 647
FAB566R
Alexa Fluor 750
FAB566S
Allophycocyanin/Cy7
FAB566APCCY7
Biotin
FAB566B
DyLight 350
FAB566D
DyLight 405
FAB566E
DyLight 488
FAB566K
DyLight 550
FAB566L
DyLight 594
FAB566M
DyLight 650
FAB566W
DyLight 680
FAB566Y
DyLight 755
FAB566Z
HRP
FAB566H
Janelia Fluor 525
FAB566JF525
Janelia Fluor 549
FAB566I
Janelia Fluor 585
FAB566JF585
Janelia Fluor 635
FAB566JF635
Janelia Fluor 646
FAB566J
Janelia Fluor 669
FAB566JF669
PE/Atto594
FAB566PEATT594
PE/Cy5.5
FAB566PECY55
PE/Cy7
FAB566PECY7
Unconjugated
MAB566
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB566
Carrier Free
MAB566
Carrier Free
MAB566-SP
Carrier Free
FAB566U-100UG
Carrier Free
FAB566T-100UG
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Neuropilin-1 Antibody (130603) [Alexa Fluor® 488] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant rat Neuropilin‑1
Phe22-Asp854 (Lys811Arg, Pro812-Gly828 del), predicted
Accession # Q9QWJ9
Specificity
Detects rat Neuropilin-1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant rat Neuropilin-2 is observed.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
NRP1
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Blockade of Receptor-ligand Interaction
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Neuropilin-1 Antibody (130603) [Alexa Fluor® 488]

  • BDCA4
  • BDCA-4
  • CD304 antigen
  • CD304
  • DKFZp686A03134
  • DKFZp781F1414
  • neuropilin 1
  • Neuropilin1
  • Neuropilin-1
  • NP1
  • NRP
  • NRP1
  • transmembrane receptor
  • Vascular endothelial cell growth factor 165 receptor
  • VEGF165R

Background

Neuropilin-1/CD304 is a type-I transmembrane protein. It forms a heterodimeric complex with vascular endothelial growth factor receptor 2, and this complex functions as a receptor for vascular endothelial growth factor. On the other hand, Neuropilin-1/CD304 forms a complex with plexin-1, and this complex acts as a semaphorin 3A receptor. Neuropilin-1/CD304 is involved in angiogenesis, axon guidance, cell survival, migration, and invasion. Recently, it has been reported that Neuropilin-1/CD304 is an essential component located on the immunological synapse and acts as a potent cell-surface marker for murine regulatory T cells (Treg). Neuropilin-1/CD304 expressed by Treg cells promotes long interactions between Treg cells and immature dendritic cells and restricts access of effector cells to the antigen-presenting cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Neuropilin-1
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FAB566G
Neuropilin-1 Antibody (130603) [Alexa Fluor® 488]
Species: Rt
Applications: Flow, B/N, CyTOF-ready

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FAQs for Neuropilin-1 Antibody (FAB566G). (Showing 1 - 2 of 2 FAQ).

  1. If this product is used in an application or species as a part of a customer review, will that validate this product in the application/species?
    • If any of our primary antibodes are used in an untested application or species and it is shown to work through images from customer reviews or through publications, this validates the application/species for this product. Please check out our Innovator's Reward Program if you decide to test an antibody with a species or application that is not currently listed.
  2. What research areas can Neuropilin-1 antibodies be used in?
    • Neuropilin-1 products can be applied in the following research areas: Adaptive Immunity, Angiogenesis, Breast Cancer, Cancer, Cardiovascular Biology, Neuroscience, and Virology Bacteria and Parasites.

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Bioinformatics

Gene Symbol NRP1