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NET1 Antibody (CL3063)

Images

 
Immunohistochemistry-Paraffin: NET1 Antibody (CL3063) [NBP2-46648] - Staining of human kidney shows no positivity in cells in tubules or glomeruli as expected.
Immunohistochemistry: NET1 Antibody (CL3063) [NBP2-46648] - Staining of rat pons shows strong positivity in noradarenaine neurons in the locus coeruleus.
Immunohistochemistry: NET1 Antibody (CL3063) [NBP2-46648] - Staining of rat cerebellum shows strong positivity in noradrenergic fibers.
Immunohistochemistry-Paraffin: NET1 Antibody (CL3063) [NBP2-46648] - Staining of human placenta shows weak membranous positivity in trophoblastic cells.
Immunohistochemistry-Paraffin: NET1 Antibody (CL3063) [NBP2-46648] - Staining of human placenta shows weak membranous positivity in trophoblastic cells.
Immunohistochemistry: NET1 Antibody (CL3063) [NBP2-46648] - Staining of mouse brain shows strong positivity in noradrenergic fibers in the cerebral cortex.
Immunohistochemistry: NET1 Antibody (CL3063) [NBP2-46648] - Staining of mouse brain shows strong positivity in noradrenergic fibers in the hippocampus.
Immunohistochemistry-Paraffin: NET1 Antibody (CL3063) [NBP2-46648] - Staining of human locus coeruleus shows strong cytoplasmic positivity in noradrenaline neurons.
Immunohistochemistry-Paraffin: NET1 Antibody (CL3063) [NBP2-46648] - Staining of human prostate shows strong positivity in sympathetic peripheral nerves.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC
Clone
CL3063
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

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NET1 Antibody (CL3063) Summary

Immunogen
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence SLYYLFSSFTLNLPWTDCGHTWNSPNCTDPKLLNGSVLGNHTKYSKYKFTPAAEFYERGVLHLHESSGIHDI
Epitope
HTKYSKYKFTPAAEF
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
NET1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
NET1 Recombinant Protein Antigen (NBP2-46648PEP)

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Protein A purified

Alternate Names for NET1 Antibody (CL3063)

  • ARHGEF8neuroepithelial cell-transforming gene 1 protein
  • guanine nucleotide regulatory protein (oncogene)
  • NET1A
  • neuroepithelial cell transforming 1
  • neuroepithelial cell transforming gene 1
  • neuroepithelioma transforming gene 1
  • p65 Net1 proto-oncogene protein
  • Proto-oncogene p65 Net1
  • Rho guanine nucleotide exchange factor (GEF) 8
  • Rho guanine nucleotide exchange factor 8
  • small GTP-binding protein regulator

Background

NET1 is a guanyl nucleotide exchange factor for RhoA GTPase. It may be involved in signal transduction, in the activation of the SAPK/JNK pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol NET1
Entrez
Uniprot