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Nectin-2/CD112 Antibody (829038) [DyLight 550]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
829038
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 550

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB3869U-100UG
Alexa Fluor 405
FAB3869V-100UG
Alexa Fluor 488
FAB3869G
Alexa Fluor 532
FAB3869X
Alexa Fluor 594
FAB3869T-100UG
Alexa Fluor 647
FAB3869R-100UG
Alexa Fluor 700
FAB3869N-100UG
Alexa Fluor 750
FAB3869S-100UG
Allophycocyanin
FAB3869A
Allophycocyanin/Cy7
FAB3869APCCY7
Biotin
FAB3869B
CoraFluor 1
FAB3869CL1
DyLight 350
FAB3869D
DyLight 405
FAB3869E
DyLight 488
FAB3869K
DyLight 594
FAB3869M
DyLight 650
FAB3869W
DyLight 680
FAB3869Y
DyLight 755
FAB3869Z
FITC
FAB3869F
HRP
FAB3869H
Janelia Fluor 525
FAB3869JF525
Janelia Fluor 549
FAB3869I
Janelia Fluor 585
FAB3869JF585
Janelia Fluor 635
FAB3869JF635
Janelia Fluor 646
FAB3869J
Janelia Fluor 669
FAB3869JF669
PE/Atto594
FAB3869PEATT594
PE/Cy5.5
FAB3869PECY55
PE/Cy7
FAB3869PECY7
PerCP
FAB3869C
Phycoerythrin
FAB3869P
Unconjugated
MAB3869
mFluor Violet 450 SE
FAB3869MFV450
mFluor Violet 500 SE
FAB3869MFV500
mFluor Violet 610 SE
FAB3869MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB3869
Carrier Free
FAB3869P
Carrier Free
MAB3869
Carrier Free
FAB3869A
Carrier Free
FAB3869G
Carrier Free
MAB3869-SP
Carrier Free
FAB3869V-100UG
Carrier Free
FAB3869U-100UG
Carrier Free
FAB3869T-100UG
Carrier Free
FAB3869S-100UG
Carrier Free
FAB3869R-100UG
Carrier Free
FAB3869N-100UG
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Nectin-2/CD112 Antibody (829038) [DyLight 550] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Nectin-2/CD112
Gln32-Gly351 (predicted)
Accession # P32507
Specificity
Detects mouse Nectin-2/CD112 in ELISAs. In direct ELISAs, no cross-reactivity with recombinant human Nectin-2 or recombinant mouse CD155/PVR is observed.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
PVRL2
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Nectin-2/CD112 Antibody (829038) [DyLight 550]

  • CD112 antigen
  • CD112
  • Herpes virus entry mediator B
  • Herpesvirus entry mediator B
  • herpesvirus entry protein B
  • HVEB
  • HVEBpoliovirus receptor-like 2
  • MPH
  • nectin 2
  • Nectin2
  • Nectin-2
  • poliovirus receptor-related 2 (herpesvirus entry mediator B)
  • poliovirus receptor-related protein 2
  • PRR2
  • PRR2nectin-2
  • PVRL2
  • PVRR2poliovirus receptor related 2

Background

Nectin 2 encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PVRL2