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MRP1 Antibody (QCRL) [mFluor Violet 450 SE]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP, CyTOF-ready, Flow, ICC/IF
Clone
QCRL
Clonality
Monoclonal
Host
Mouse
Conjugate
mFluor Violet 450 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC19291U-100UG
Alexa Fluor 405
IC19291V-100UG
Alexa Fluor 488
IC19291G-100UG
Alexa Fluor 532
FAB19291X
Alexa Fluor 594
IC19291T-100UG
Alexa Fluor 647
IC19291R-100UG
Alexa Fluor 700
IC19291N-100UG
Alexa Fluor 750
IC19291S-100UG
Allophycocyanin
FAB19291A
Biotin
FAB19291B
CoraFluor 1
FAB19291CL1
DyLight 350
FAB19291D
DyLight 405
FAB19291E
DyLight 488
FAB19291K
DyLight 550
FAB19291L
DyLight 594
FAB19291M
DyLight 650
FAB19291W
DyLight 680
FAB19291Y
DyLight 755
FAB19291Z
FITC
FAB19291F
HRP
FAB19291H
Janelia Fluor 525
FAB19291JF525
Janelia Fluor 549
FAB19291I
Janelia Fluor 585
FAB19291JF585
Janelia Fluor 635
FAB19291JF635
Janelia Fluor 646
FAB19291J
Janelia Fluor 669
FAB19291JF669
PerCP
FAB19291C
Phycoerythrin
IC19291P
Unconjugated
MAB19291
mFluor Violet 500 SE
FAB19291MFV500
mFluor Violet 610 SE
FAB19291MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB19291
Carrier Free
IC19291P
Carrier Free
MAB19291
Carrier Free
MAB19291-SP
Carrier Free
IC19291V-100UG
Carrier Free
IC19291U-100UG
Carrier Free
IC19291T-100UG
Carrier Free
IC19291S-100UG
Carrier Free
IC19291R-100UG
Carrier Free
IC19291N-100UG
Carrier Free
IC19291G-100UG
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MRP1 Antibody (QCRL) [mFluor Violet 450 SE] Summary

Immunogen
H69AR human small cell lung cancer cell line membrane extracts
Specificity
Detects human MRP1 in direct ELISAs and Western blots.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ABCC1
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Immunocytochemistry
  • Immunoprecipitation
  • Intracellular Staining by Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for MRP1 Antibody (QCRL) [mFluor Violet 450 SE]

  • ABC29
  • ABCC
  • ABCC1
  • ATP-binding cassette sub-family C member 1
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • EC 3.6.3
  • EC 3.6.3.44
  • GS-X
  • Leukotriene C(4) transporter
  • LTC4 transporter
  • MRP1
  • MRP1DKFZp781G125
  • MRPDKFZp686N04233
  • multidrug resistance associated protein 1
  • multidrug resistance protein
  • multidrug resistance-associated protein 1
  • multiple drug resistance protein 1
  • multiple drug resistance-associated protein

Background

Multidrug Resistance Protein 1 (MRP1) is an integral membrane glycophosphoprotein belonging to the same superfamily of ATP-binding cassette transmembrane transporter proteins as P-glycoprotein. MRP1 is overexpressed in many P-glycoprotein-negative, multidrug resistant cell lines and tumours. It is believed that the main function of MRP in drug resistance is that of a plasma membrane drug efflux pump.

Specifically, MRP1 mediates the export of organic anions and drugs from the cytoplasm. It is through this function, that MRP1 is able to confer resistance to anticancer drugs. MRP1 antibodies are therefore useful tools for cancer testing and research.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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ABC Membrane transporters and the role of MRP1 in drug resistance
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Bioinformatics

Gene Symbol ABCC1