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MRP1 Antibody (QCRL) [DyLight 594]

Name: MRP1 Antibody (QCRL) [DyLight 594]
Brand: Novus Biologicals
SKU: FAB19291M
Price: 529 USD

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Product Details

Summary

Reactivity	HuSpecies Glossary
Applications	WB, IP, CyTOF-ready, Flow, ICC/IF
Clone	QCRL
Clonality	Monoclonal
Host	Mouse
Conjugate	DyLight 594

Order Details

View Available Conjugates

Catalog# & Conjugate	Size	Price
Alexa Fluor 350 IC19291U-100UG

Alexa Fluor 405 IC19291V-100UG

Alexa Fluor 488 IC19291G-100UG

Alexa Fluor 532 FAB19291X

Alexa Fluor 594 IC19291T-100UG

Alexa Fluor 647 IC19291R-100UG

Alexa Fluor 700 IC19291N-100UG

Alexa Fluor 750 IC19291S-100UG

Allophycocyanin FAB19291A

Biotin FAB19291B

CoraFluor 1 FAB19291CL1

DyLight 350 FAB19291D

DyLight 405 FAB19291E

DyLight 488 FAB19291K

DyLight 550 FAB19291L

DyLight 650 FAB19291W

DyLight 680 FAB19291Y

DyLight 755 FAB19291Z

FITC FAB19291F

HRP FAB19291H

Janelia Fluor 525 FAB19291JF525

Janelia Fluor 549 FAB19291I

Janelia Fluor 585 FAB19291JF585

Janelia Fluor 635 FAB19291JF635

Janelia Fluor 646 FAB19291J

Janelia Fluor 669 FAB19291JF669

PerCP FAB19291C

Phycoerythrin IC19291P

Unconjugated MAB19291

mFluor Violet 450 SE FAB19291MFV450

mFluor Violet 500 SE FAB19291MFV500

mFluor Violet 610 SE FAB19291MFV610

View Available Formulations

Catalog# & Formulation	Size	Price
Standard Formulation MAB19291

Carrier Free IC19291P

Carrier Free MAB19291

Carrier Free MAB19291-SP

Carrier Free IC19291V-100UG

Carrier Free IC19291U-100UG

Carrier Free IC19291T-100UG

Carrier Free IC19291S-100UG

Carrier Free IC19291R-100UG

Carrier Free IC19291N-100UG

Carrier Free IC19291G-100UG

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Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	IC19291U-100UG
Alexa Fluor 405	IC19291V-100UG
Alexa Fluor 488	IC19291G-100UG
Alexa Fluor 532	FAB19291X
Alexa Fluor 594	IC19291T-100UG
Alexa Fluor 647	IC19291R-100UG
Alexa Fluor 700	IC19291N-100UG
Alexa Fluor 750	IC19291S-100UG
Allophycocyanin	FAB19291A
Biotin	FAB19291B
CoraFluor 1	FAB19291CL1
DyLight 350	FAB19291D
DyLight 405	FAB19291E
DyLight 488	FAB19291K
DyLight 550	FAB19291L
DyLight 650	FAB19291W
DyLight 680	FAB19291Y
DyLight 755	FAB19291Z
FITC	FAB19291F
HRP	FAB19291H
Janelia Fluor 525	FAB19291JF525
Janelia Fluor 549	FAB19291I
Janelia Fluor 585	FAB19291JF585
Janelia Fluor 635	FAB19291JF635
Janelia Fluor 646	FAB19291J
Janelia Fluor 669	FAB19291JF669
PerCP	FAB19291C
Phycoerythrin	IC19291P
Unconjugated	MAB19291
mFluor Violet 450 SE	FAB19291MFV450
mFluor Violet 500 SE	FAB19291MFV500
mFluor Violet 610 SE	FAB19291MFV610

MRP1 Antibody (QCRL) [DyLight 594] Summary

Immunogen	H69AR human small cell lung cancer cell line membrane extracts
Specificity	Detects human MRP1 in direct ELISAs and Western blots.
Isotype	IgG1
Clonality	Monoclonal
Host	Mouse
Gene	ABCC1
Purity	Protein A or G purified from hybridoma culture supernatant
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Applications/Dilutions

Dilutions	CyTOF-ready Immunocytochemistry Immunoprecipitation Intracellular Staining by Flow Cytometry Western Blot
Application Notes	Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage	Store at 4C in the dark.
Buffer	50mM Sodium Borate
Preservative	0.05% Sodium Azide
Purity	Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for MRP1 Antibody (QCRL) [DyLight 594]

ABC29
ABCC
ABCC1
ATP-binding cassette sub-family C member 1
ATP-binding cassette, sub-family C (CFTR/MRP), member 1
EC 3.6.3
EC 3.6.3.44
GS-X
Leukotriene C(4) transporter
LTC4 transporter
MRP1
MRP1DKFZp781G125
MRPDKFZp686N04233
multidrug resistance associated protein 1
multidrug resistance protein
multidrug resistance-associated protein 1
multiple drug resistance protein 1
multiple drug resistance-associated protein

Background

Multidrug Resistance Protein 1 (MRP1) is an integral membrane glycophosphoprotein belonging to the same superfamily of ATP-binding cassette transmembrane transporter proteins as P-glycoprotein. MRP1 is overexpressed in many P-glycoprotein-negative, multidrug resistant cell lines and tumours. It is believed that the main function of MRP in drug resistance is that of a plasma membrane drug efflux pump.

Specifically, MRP1 mediates the export of organic anions and drugs from the cytoplasm. It is through this function, that MRP1 is able to confer resistance to anticancer drugs. MRP1 antibodies are therefore useful tools for cancer testing and research.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for MRP1 Antibody (FAB19291M) (0)

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Product General Protocols

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Secondary Antibodies

Isotype Controls

Additional MRP1 Products

Research Areas for MRP1 Antibody (FAB19291M)

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Blogs on MRP1.

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ABC Membrane transporters and the role of MRP1 in drug resistance
ATP-binding cassette (ABC) transporters, alongside ion channels and aquaporins, are ubiquitous membrane-bound proteins that move substrates across extra and intra cellular membranes. Multidrug resistance-associated protein 1 (MRP1) is a member o... Read full blog post.

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CFTR was detected in immersion fixed paraffin-embedded sections of human placenta using 8 µg/mL Mouse Anti-Human CFTR C-Terminus Monoclonal Antibody (Catalog # MAB25031) overnight at 4 °C. Tissue was stained with the Anti-Mouse HRP-AEC Cell & Tissue Staining Kit (red; Catalog # CTS003) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

CFTR Antibody (24-1) [Unconjugated] - C-terminus
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Bioinformatics

Gene Symbol

ABCC1

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

MRP1 Antibody (QCRL) [DyLight 594]

Species Glossary

Images

Product Details

Order Details

MRP1 Antibody (QCRL) [DyLight 594] Summary

Applications/Dilutions

Packaging, Storage & Formulations

Notes

Alternate Names for MRP1 Antibody (QCRL) [DyLight 594]

Background

Limitations

Customers Who Viewed This Item Also Viewed...

Publications for MRP1 Antibody (FAB19291M) (0)

Reviews for MRP1 Antibody (FAB19291M) (0)

Product General Protocols

Video Protocols

FAQs for MRP1 Antibody (FAB19291M) (0)

Secondary Antibodies

Isotype Controls

Additional MRP1 Products

Research Areas for MRP1 Antibody (FAB19291M)

Blogs on MRP1.

Customers Who Bought This Also Bought

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Product PDFs

Calculators

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Bioinformatics