M6II-7 can be used to detect human MRP6 in cells and tissues. Immunocytochemistry: use 1:20-50 dilution on acetone fixed cytospin preparations. For immunohistochemistry: M6II-7 (use 1:20-50) on acetone fixed frozen sections can be followed by incubation w
Publications
Read Publication using NBP1-42342 in the following applications:
ATP-binding cassette, sub-family C (CFTR/MRP), member 6
EST349056
MLP1ABC34
MOATE
MOAT-E
MRP6ATP-binding cassette sub-family C member 6
multidrug resistance-associated protein 6
Multi-specific organic anion transporter E
pseudoxanthoma elasticum
PXE1
URG7
Background
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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