MLH3 Antibody Summary
Immunogen |
Peptide with sequence RQSLQQSMPPCEPP corresponding to C-Terminus according to NP_001035197.1, NP_055196.2. |
Specificity |
This antibody is expected to recognize isoform 1 (NP_001035197.1) and isoform 2 (NP_055196.2). |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Goat |
Gene |
MLH3 |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Flow Cytometry 10 ug/mL
- Immunocytochemistry/ Immunofluorescence 10 ug/mL
- Peptide ELISA Detection limit 1:2000
|
Packaging, Storage & Formulations
Storage |
Store at -20C. Avoid freeze-thaw cycles. |
Buffer |
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA |
Preservative |
0.02% Sodium Azide |
Purity |
Immunogen affinity purified |
Alternate Names for MLH3 Antibody
Background
This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Product General Protocols
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FAQs for MLH3 Antibody (NBP2-78702) (0)
Secondary Antibodies
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