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M-CSFR/CD115 Antibody (61708) [Biotin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
61708
Clonality
Monoclonal
Host
Mouse
Conjugate
Biotin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB329U-100UG
Alexa Fluor 405
FAB329V-100UG
Alexa Fluor 488
FAB329G-100UG
Alexa Fluor 532
FAB329X
Alexa Fluor 594
FAB329T-100UG
Alexa Fluor 647
FAB329R-100UG
Alexa Fluor 700
FAB329N-025
Alexa Fluor 700
FAB329N-100
Alexa Fluor 750
FAB329S-100UG
Allophycocyanin
FAB329A-025
Allophycocyanin
FAB329A-100
Allophycocyanin/Cy7
FAB329APCCY7
DyLight 350
FAB329D
DyLight 405
FAB329E
DyLight 488
FAB329K
DyLight 550
FAB329L
DyLight 594
FAB329M
DyLight 650
FAB329W
DyLight 680
FAB329Y
DyLight 755
FAB329Z
HRP
FAB329H
Janelia Fluor 549
FAB329I
Janelia Fluor 646
FAB329J
PE/Atto594
FAB329PEATT594
PE/Cy5.5
FAB329PECY55
PE/Cy7
FAB329PECY7
PerCP
FAB329C
Phycoerythrin
FAB329P-100
Phycoerythrin
FAB329P-025
Unconjugated
MAB329
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB329
Carrier Free
MAB329
Carrier Free
MAB329-SP
Carrier Free
FAB329A-100
Carrier Free
FAB329A-025
Carrier Free
FAB329N-100
Carrier Free
FAB329N-025
Carrier Free
FAB329P-100
Carrier Free
FAB329P-025
Carrier Free
FAB329V-100UG
Carrier Free
FAB329U-100UG
Carrier Free
FAB329T-100UG
Carrier Free
FAB329S-100UG
Carrier Free
FAB329R-100UG
Carrier Free
FAB329G-100UG
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M-CSFR/CD115 Antibody (61708) [Biotin] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human M-CSF R/CD115
Ile20-Glu512 (Pro54Ala)
Accession # P07333.2
Specificity
Detects human M-CSF R/CD115 in direct ELISAs and Western blots. Does not cross-react with recombinant human (rh) GM-CSF R alpha or
rhGM-CSF R beta .
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CSF1R
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for M-CSFR/CD115 Antibody (61708) [Biotin]

  • CD115 antigen
  • CD115
  • c-fms
  • colony stimulating factor 1 receptor
  • CSF1R
  • CSF-1-R
  • CSFR
  • EC 2.7.10.1
  • FMS proto-oncogene
  • FMSFIM2
  • macrophage colony stimulating factor I receptor
  • macrophage colony-stimulating factor 1 receptor
  • McDonough feline sarcoma viral (v-fms) oncogene homolog
  • M-CSF R
  • MCSFR
  • M-CSFR
  • Proto-oncogene c-Fms

Background

MCSF Receptor is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a member of the CSF1/PDGF receptor family of tyrosine protein kinases and contains 5 immunoglobulin like C2 type domains. CD115 is expressed by cells of the monocytic lineage and by progenitor cells. Mutations in this gene have been associated with a predisposition to myeloid malignancy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for M-CSFR/CD115 Antibody (FAB329B) (0)

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Secondary Antibodies

 

Isotype Controls

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Research Areas for M-CSFR/CD115 Antibody (FAB329B)

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Blogs on M-CSFR/CD115

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Contact Information

Product PDFs

  SDS
  PDF Datasheet
  Request CofA

Calculators

Concentration Calculator

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Bioinformatics

Gene Symbol CSF1R