Liprin alpha 1 Antibody - BSA Free Summary
Immunogen |
The immunogen for this antibody was a sequence from 310a.a. to 360a.a. from Liprin-alpha-1(a 1202a.a. long protein) |
Localization |
Cytoplasm. Colocalizes with PTPRF at the ends of focal adhesions most proximal to the cell nucleus. |
Specificity |
Liprin-alpha-1 |
Clonality |
Polyclonal |
Host |
Chicken |
Gene |
PPFIA1 |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Western Blot 1:200- 1:500
|
Application Notes |
Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000. Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. |
Reactivity Notes
This antibody is reactive against Human, mouse, rat.
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
PBS |
Preservative |
0.02% Sodium Azide |
Purity |
Immunogen affinity purified |
Notes
Chicken products cannot be exported to Canada.
Alternate Names for Liprin alpha 1 Antibody - BSA Free
Background
Liprin alpha 1 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane. possibly regulating their interaction with the extracellular environment and their association with substrates.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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