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Kir3.1 Antibody

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Immunohistochemistry-Paraffin: Kir3.1 Antibody [NBP1-32958] - Paraffin-embedded DU145 xenograft, using antibody at 1:100 dilution.

Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, Ch, Gp, RMSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Kir3.1 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human Kir3.1. The exact sequence is proprietary.
Localization
Membrane, Multi-pass membrane protein
Predicted Species
Rat (98%), Chicken (91%), Bovine (99%), Guinea Pig (99%), Rhesus Macaque (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KCNJ3
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
Theoretical MW
57 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7), 20% Glycerol
Preservative
0.025% Proclin 300
Purity
Antigen Affinity-purified

Alternate Names for Kir3.1 Antibody

  • G protein-activated inward rectifier potassium channel 1
  • GIRK1
  • GIRK-1
  • GIRK1Kir3.1
  • Inward rectifier K(+) channel Kir3.1
  • inward rectifier K+ channel KIR3.1
  • KCNJ3
  • KGA
  • Kir3.1
  • Potassium channel, inwardly rectifying subfamily J member 3
  • potassium inwardly-rectifying channel, subfamily J, member 3

Background

FUNCTION: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.; Subcellular location: Membrane, Multi-pass membrane protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol KCNJ3
Entrez
Uniprot