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KIR2DS5/CD158g Antibody (1165A) [DyLight 594]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
1165A
Clonality
Monoclonal
Host
Rabbit
Conjugate
DyLight 594

Order Details

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KIR2DS5/CD158g Antibody (1165A) [DyLight 594] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
NS0 mouse myeloma cell line transfected with human KIR2DS5/CD158g
His22-His245
Accession # Q14953
Specificity
Detects human KIR2DS5/CD158g in direct ELISAs.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
KIR2DS5
Purity
Protein A or G purified from cell culture supernatant
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from cell culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for KIR2DS5/CD158g Antibody (1165A) [DyLight 594]

  • killer cell immunoglobulin-like receptor 2DS5
  • CD158g
  • killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
  • KIR2DS5
  • NKAT9

Background

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol KIR2DS5