Kir2.1 Antibody (2153C) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Human Inward Rectifier Potassium Channel 2 (KIR2.1), also known as KCNJ2, is a 427 amino acid (aa) integral membrane protein with 98% homology with mouse and rat KIR2.1.   This potassium channel preferentially allows potassium to flow into the cell, which is thought to generate action potential waveform and excitability in neuronal and muscle tissues. Mutations in the KIR2.1 gene are associated with Andersen syndrome, with associated paralysis, cardiac arrhythmias and dysmorphic features. KIR2.1 is widely expressed, notably in heart, placenta, lung, skeletal muscle, kidney and spleen. Expression of KIR2.1 is necessary for development of mature cardiomyocytes from mouse embryonic stem cells.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 1 application: Western Blot.

Showing Publications 1 - 2 of 2.

Publications using MAB9548	Applications	Species
W Yu, Z Wang, X Yu, Y Zhao, Z Xie, K Zhang, Z Chi, S Chen, T Xu, D Jiang, X Guo, M Li, J Zhang, H Fang, D Yang, Y Guo, X Yang, X Zhang, Y Wu, W Yang, D Wang Kir2.1-mediated membrane potential promotes nutrient acquisition and inflammation through regulation of nutrient transporters Nature Communications, 2022-06-21;13(1):3544. 2022-06-21 [PMID: 35729093] (Western Blot, Mouse)	Western Blot	Mouse
A Di Baldass, MA D'Amico, P Izzicupo, G Gaggi, S Guarnieri, MA Mariggiò, I Antonucci, B Corneo, D Sirabella, L Stuppia, B Ghinassi Cardiomyocytes Derived from Human CardiopoieticAmniotic Fluids Sci Rep, 2018-08-13;8(1):12028. 2018-08-13 [PMID: 30104705] (Western Blot, Human)	Western Blot	Human

Array MAB9548

• Kir2.1 Antibodies
• Kir2.1 Proteins