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ILT1/CD85h/LILRA2 Antibody (600007) [DyLight 755]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
600007
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 755

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ILT1/CD85h/LILRA2 Antibody (600007) [DyLight 755] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human LILRA2/CD85h/ILT1
Pro17-Ser437
Accession # Q8N149
Specificity
Detects human LILRA2/CD85h/ILT1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) ILT2, 3, 4, 5, rhLIR6, or rhLIR8 is observed.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
LILRA2
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for ILT1/CD85h/LILRA2 Antibody (600007) [DyLight 755]

  • CD85 antigen-like family member H
  • CD85h antigen
  • CD85h
  • ILT1
  • ILT-1
  • ILT1CD85H
  • Leukocyte immunoglobulin-like receptor 7
  • leukocyte immunoglobulin-like receptor subfamily A member 2 soluble
  • leukocyte immunoglobulin-like receptor subfamily A member 2
  • leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
  • LILRA2
  • LIR7
  • LIR7LIR-7Immunoglobulin-like transcript 1

Background

LILRA2, also known as Leukocyte immunoglobulin-like receptor subfamily A member 2, has a 483 amino acid long isoform that is 53 kDa and a short 466 amino acid isoform that is 51 kDa, acts as an activating receptor for eosinophils that elicited the release of cytotoxic granule proteins, de novo lipid mediator generation, and cytokine release through vesicular transport, but does not bind class I MHC antigens. Studies are being performed in relation to this protein and several diseases and disorders including leprosy, microscopic polyangiitis, systemic lupus, erythematosus, lupus erythematosus, hepatitis c, and hepatitis b. This protein has been shown to interact with EWSR1 and USP46 proteins in osteoclast differentiation, defense response, and signal transduction pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol LILRA2