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IL-4 Antibody (11B11) [Alexa Fluor® 350] - Chimeric

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IL-4 Antibody (11B11) [Alexa Fluor® 350] - Chimeric [NBP2-52656AF350] - Vial of Alexa Fluor 350 conjugated antibody. Alexa Fluor 350 is optimally excited at 346 nm by the UV laser (350 or 355 nm) and has an ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA, Flow, Func, IHC, CyTOF-ready
Clone
11B11
Clonality
Monoclonal
Host
Rabbit
Conjugate
Alexa Fluor 350

Order Details

IL-4 Antibody (11B11) [Alexa Fluor® 350] - Chimeric Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
BSF-1 / IL-4 purified from serum-free supernatants of cultured EL-4 cells (a C57BL/6 thymoma) induced with 4 Beta-phorbol 12 Beta-myristate 12 alpha -acetate for 48h.
Specificity
Binds to a core functional region of murine IL-4, which prevents this cytokine from interacting with its cognate receptor (Yao et al., 2006 PMID: 16361318).
Isotype
IgG Kappa
Clonality
Monoclonal
Host
Rabbit
Gene
IL4
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • ELISA
  • Flow Cytometry
  • Immunohistochemistry
  • In vivo assay
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Mouse

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for IL-4 Antibody (11B11) [Alexa Fluor® 350] - Chimeric

  • B cell growth factor 1
  • BCDF
  • B-cell stimulatory factor 1
  • BCGF1
  • BCGF-1
  • binetrakin
  • BSF1
  • BSF-1
  • IL4
  • IL-4
  • IL-4B_cell stimulatory factor 1
  • IL4E12
  • interleukin 4
  • interleukin-4
  • Lymphocyte stimulatory factor 1
  • MGC79402
  • pitrakinra

Background

IL-4 (Interleukin 4, B cell stimulatory factor) is a pleiotropic cytokine produced by activated T cells, mast cells and basophils. IL-4 has many different functions including promoting proliferation and differentiation of immunologically competent cells. One of its main functions is regulating differentiation of naive CD4+ T cells into helper Th2 cells, the other main function is regulating B cells IgE and IgG1 production. Human IL-4 shows 50% homology with mouse IL-4, but its activities are species-specific and human IL-4 shows no activity on murine and rat cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Blogs on IL-4.

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Bioinformatics

Gene Symbol IL4