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IGSF2/CD101 Antibody (307707) [DyLight 755]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
307707
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 755

Order Details

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IGSF2/CD101 Antibody (307707) [DyLight 755] Summary

Immunogen
Chinese hamster ovary cell line CHO-derived recombinant mouse IGSF2/CD101
Gln21-Tyr1033
Accession # A8E0Y8
Specificity
Detects mouse IGSF2/CD101.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
CD101
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for IGSF2/CD101 Antibody (307707) [DyLight 755]

  • CD101 antigen
  • CD101 molecule
  • CD101
  • Cell surface glycoprotein V7
  • EWI101
  • EWI-101
  • Glu-Trp-Ile EWI motif-containing protein 101
  • IGSF2
  • Leukocyte Surface Protein
  • member 2
  • V7

Background

CD101 is a disulfide-linked homodimeric type 1 glycoprotein. The peptide is comprised of 7 extracellular V-type IgSF domains. CD101 is highly expressed on monocytes, granulocytes, mucosal T cells, and on activated peripheral blood T cells. Expression is weak on resting T and B and NK cells, absent from platelets and weak or absent from most hematopoietic cell lines. CD101 is thought to play a co-stimulatory role in TCR/CD3-mediated T cell activation. Monoclonal antibodies against CD101 inhibit allogeneic T cell responses. Studies suggest that CD101 plays a major role in the activation of T cells by skin dendritic cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CD101