HPx1 Antibody (HIC0-3B3)

Stem cells offer a therapeutic promise for many diseases. In the case of diabetes, stem cells offer the promise that beta cells may be generated ex vivo for the possible transplantation and cure of Type I diabetes (Couri CE, et al.). For this to happen, stem cells will need to be isolated and expanded, they will need to be differentiated toward the beta cell lineage, and the differentiated cell progeny used for transplantation may need to be isolated from complex cell mixtures following differentiation. Appropriate markers targeting cell surface molecules on developing and mature pancreatic cells will be required for such research.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: FLOW, IHC-Fr, WB.

Showing Publications 1 - 10 of 11. Show All 11 Publications. Collapse Publications.

Publications using NBP1-18951	Applications	Species
Ma H, Jeppesen JF, Jaenisch R. Et al. Human T Cells Expressing a CD19 CAR-T Receptor Provide Insights into Mechanisms of Human CD19-Positive b Cell Destruction Cell Rep Med 2020-11-18 [PMID: 33205073] Details: Citation using the DyLight 488 version of this antibody.
Camunas-Soler, J, Dai, X Q Et al. Patch-Seq Links Single-Cell Transcriptomes to Human Islet Dysfunction in Diabetes. Cell Metab 2020-05-05 [PMID: 32302527] (WB, Human)	WB	Human
Arda H, Tsai J, Rosli Y et al A Chromatin Basis for Cell Lineage and Disease Risk in the Human Pancreas Cell Syst 2018-08-27 [PMID: 30145115] (FLOW, Human) Details: Citation using the DyLight 488 version of this antibody.	FLOW	Human
Jakel C, Bergmann F, Toth R et al. Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability Nat Commun. 2017-11-06 [PMID: 29109526] (Human)		Human
Enge M, Arda HE, Mignardi M et al. Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns. Autophagy. 2017-05-04 [PMID: 28965763] (Human) Details: Citation used the DyLight 650 format of this antibody.		Human
Cogger KF, Sinha A, Sarangi F et al. Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors Nat Commun 2017-08-24 [PMID: 28835709] (FLOW, Human)	FLOW	Human
Arda HE, Li L, Tsai J, et al. Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human beta Cell Function. Cell Press. 2016-05-10 [PMID: 27133132] (FLOW, Human)	FLOW	Human
Nostro MC, Sarangi F, Ogawa S et al. Pancreatic differentiation 2008-01-01 [PMID: 23658992]
Dorrell C, Schug J, Lin C et al. Transcriptomes of the major human pancreatic cell types. Diabetologia. 2011-01-01 [PMID: 21882062]
Nostro MC, Sarangi F, Ogawa S, Holtzinger A, Corneo B, Li X, Micallef SJ, Park IH, Basford C, Wheeler MB, Daley GQ, Elefanty AG, Stanley EG, Keller G. Stage-specific signaling through TGFbeta family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells. Development;138(5):861-71. 2011-03-01 [PMID: 21270052] (FLOW, Human)	FLOW	Human
Dorrell, et al. Isolation of major pancreatic cell types long-term culture-initiating cells using novel human surface markers. Stem Cell Rsch 1(3):183-194. 2008-01-01 [PMID: 19383399] (FLOW, IHC-Fr, Human)	FLOW, IHC-Fr	Human
Show All 11 Publications. Collapse Publications.

Array NBP1-18951

• HPx1 Antibodies