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HERV Antibody [Janelia Fluor® 525]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Func, IHC, B/N
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 525

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-93579AF350
Alexa Fluor 405
NB100-93579AF405
Alexa Fluor 488
NB100-93579AF488
Alexa Fluor 532
NB100-93579AF532
Alexa Fluor 594
NB100-93579AF594
Alexa Fluor 647
NB100-93579AF647
Alexa Fluor 700
NB100-93579AF700
Alexa Fluor 750
NB100-93579AF750
Allophycocyanin
NB100-93579APC
Biotin
NB100-93579B
CoraFluor 1
NB100-93579CL1
DyLight 350
NB100-93579UV
DyLight 405
NB100-93579V
DyLight 488
NB100-93579G
DyLight 550
NB100-93579R
DyLight 594
NB100-93579DL594
DyLight 650
NB100-93579C
DyLight 680
NB100-93579FR
DyLight 755
NB100-93579IR
FITC
NB100-93579F
HRP
NB100-93579H
Janelia Fluor 549
NB100-93579JF549
Janelia Fluor 585
NB100-93579JF585
Janelia Fluor 635
NB100-93579JF635
Janelia Fluor 646
NB100-93579JF646
Janelia Fluor 669
NB100-93579JF669
PE
NB100-93579PE
PerCP
NB100-93579PCP
Unconjugated
NB100-93579
mFluor Violet 450 SE
NB100-93579MFV450
mFluor Violet 500 SE
NB100-93579MFV500
mFluor Violet 610 SE
NB100-93579MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB100-93579
BSA Free
NB100-93579SS
BSA Free
NB100-93579
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HERV Antibody [Janelia Fluor® 525] Summary

Immunogen
Synthetic peptide corresponding to residues 42-50 [QRPGNIDAPC] of the HERV protein.
Specificity
Human Endogenous Retroviruses (HERVs), a class of multiple-sclerosis-associated retroviruses
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ERVW-1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Block/Neutralize
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • In vitro assay
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for HERV Antibody [Janelia Fluor® 525]

  • endogenous retroviral family W, env(C7), member 1
  • ENV
  • envelope glycoprotein
  • Envelope polyprotein gPr73
  • enverin
  • ENVW
  • Env-W
  • HERV-7q Envelope protein
  • HERV7Q
  • HERV-7q
  • HERV-tryptophan envelope protein
  • HERV-W Env glycoprotein
  • HERV-W envelope protein
  • HERV-W
  • HERV-W_7q21.2 provirus ancestral Env polyprotein
  • HERV-W{7q21.1} provirus ancestral Env polyprotein
  • HERVWENV
  • HERV-W-ENV
  • HERVWenvelope protein
  • human endogenous retrovirus W envC7-1 envelope protein
  • syncytin A
  • Syncytin
  • syncytin-1

Background

HERVs are a class of multiple sclerosis associated retroviruses. Reacts with a replication competent Human Endogenous Retrovirus (HERVW) isolated from placenta. The synthetic peptide sequence used as immunogen is taken from the virus envelope polyprotein sequence. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. The HERVW endogenous envelope protein has retained its original fusogenic properties and participates in trophoblast fusion during placenta morphogenesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ERVW-1