| Reactivity | HuSpecies Glossary |
| Applications | IHC |
| Clone | GH/4886R |
| Clonality | Monoclonal |
| Host | Rabbit |
| Conjugate | Allophycocyanin |
| Additional Information | Recombinant Monoclonal Antibody |
| Immunogen | Recombinant full-length human Growth Hormone protein (Uniprot: P01241 ) |
| Localization | Cytoplasm |
| Marker | Pituitary Marker |
| Specificity | Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly). |
| Isotype | IgG |
| Clonality | Monoclonal |
| Host | Rabbit |
| Gene | GH1 |
| Purity | Protein A or G purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Dilutions |
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| Application Notes | Optimal dilution of this antibody should be experimentally determined. |
| Storage | Store at 4C in the dark. |
| Buffer | PBS |
| Preservative | 0.05% Sodium Azide |
| Purity | Protein A or G purified |
Secondary Antibodies |
Isotype Controls |
Research Areas for Growth Hormone Antibody (NBP3-14007APC)Find related products by research area.
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Growth hormone (GH, somatotropin, hGH, pituitary growth hormone) GH is a member of the large family of growth factors that includes prolactin, placental lactogens, proliferins, and somatolactin. Additionally, GH is a 191-amino acid, single-chain polypeptide that is synthesized, stored, and secreted by somatotropic ... Read full blog post. |
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Somatostatin Receptor 2: Treating Patients Who Cannot Stop Growing Acromegaly is a rare life-shortening disease caused by elevated levels of growth hormone (GH) secreted by a tumor on the pituitary gland. Treatments include somatostatin analogs, which activate somatostatin receptor 2 (SSTR2), reducing GH secretion an... Read full blog post. |
The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.
| Gene Symbol | GH1 |
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