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Fetal Hemoglobin Antibody [DyLight 680]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Sheep
Conjugate
DyLight 680

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB110-41084AF350
Alexa Fluor 405
NB110-41084AF405
Alexa Fluor 488
NB110-41084AF488
Alexa Fluor 532
NB110-41084AF532
Alexa Fluor 594
NB110-41084AF594
Alexa Fluor 647
NB110-41084AF647
Alexa Fluor 700
NB110-41084AF700
Alexa Fluor 750
NB110-41084AF750
Allophycocyanin
NB110-41084APC
Biotin
NB110-41084B
DyLight 350
NB110-41084UV
DyLight 405
NB110-41084V
DyLight 488
NB110-41084G
DyLight 550
NB110-41084R
DyLight 594
NB110-41084DL594
DyLight 650
NB110-41084C
DyLight 755
NB110-41084IR
FITC
NB110-41084F
HRP
NB110-41084H
HRP
NBP3-09055
Janelia Fluor 525
NB110-41084JF525
Janelia Fluor 549
NB110-41084JF549
Janelia Fluor 585
NB110-41084JF585
Janelia Fluor 635
NB110-41084JF635
Janelia Fluor 646
NB110-41084JF646
Janelia Fluor 669
NB110-41084JF669
PE
NB110-41084PE
PerCP
NB110-41084PCP
Unconjugated
NB110-41084
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB110-41084
BSA Free
NB110-41084
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Fetal Hemoglobin Antibody [DyLight 680] Summary

Immunogen
Purified human hemoglobin F of fetal cord blood cell origin.
Specificity
By immunoelectrophoresis and ELISA this antibody reacts specifically with human hemoglobin F. No antibody was detected against hemoglobin A1, A2, S or human serum proteins.
Isotype
IgG
Clonality
Polyclonal
Host
Sheep
Gene
HBG1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Fetal Hemoglobin Antibody [DyLight 680]

  • abnormal hemoglobin
  • A-gamma globin
  • gamma A hemoglobin
  • gamma globin
  • gamma-1-globin
  • gamma-2-globin
  • gamma-globin chain
  • G-gamma globin Paulinia
  • Hb F Agamma
  • hb F Ggamma
  • HBGA
  • HBGR
  • HBG-T1
  • HBG-T2
  • Hemoglobin gamma-1 chain
  • hemoglobin gamma-2 chain
  • Hemoglobin gamma-A chain
  • hemoglobin gamma-G chain
  • hemoglobin subunit gamma-1
  • hemoglobin subunit gamma-2
  • hemoglobin, gamma A
  • hemoglobin, gamma, regulator of
  • HSGGL1
  • methemoglobin
  • PRO2979

Background

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Bioinformatics

Gene Symbol HBG1