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Exosome component 10 Antibody [Janelia Fluor® 669]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 669

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-97516AF350
Alexa Fluor 405
NBP2-97516AF405
Alexa Fluor 488
NBP2-97516AF488
Alexa Fluor 532
NBP2-97516AF532
Alexa Fluor 594
NBP2-97516AF594
Alexa Fluor 647
NBP2-97516AF647
Alexa Fluor 700
NBP2-97516AF700
Alexa Fluor 750
NBP2-97516AF750
Allophycocyanin
NBP2-97516APC
Biotin
NBP2-97516B
CoraFluor 1
NBP2-97516CL1
DyLight 350
NBP2-97516UV
DyLight 405
NBP2-97516V
DyLight 488
NBP2-97516G
DyLight 550
NBP2-97516R
DyLight 594
NBP2-97516DL594
DyLight 650
NBP2-97516C
DyLight 680
NBP2-97516FR
DyLight 755
NBP2-97516IR
FITC
NBP2-97516F
HRP
NBP2-97516H
Janelia Fluor 525
NBP2-97516JF525
Janelia Fluor 549
NBP2-97516JF549
Janelia Fluor 585
NBP2-97516JF585
Janelia Fluor 635
NBP2-97516JF635
Janelia Fluor 646
NBP2-97516JF646
PE
NBP2-97516PE
PerCP
NBP2-97516PCP
Unconjugated
NBP2-97516-100ul
mFluor Violet 450 SE
NBP2-97516MFV450
mFluor Violet 500 SE
NBP2-97516MFV500
mFluor Violet 610 SE
NBP2-97516MFV610
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Exosome component 10 Antibody [Janelia Fluor® 669] Summary

Immunogen
Produced in rabbits immunized with E. coli-derived Human Exosome component 10 fragment.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
EXOSC10
Purity
Antigen and protein A Affinity-purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Exosome component 10 Antibody [Janelia Fluor® 669]

  • autoantigen PM-SCL
  • EC 3.1.13.-
  • exosome component 10
  • P100 polymyositis-scleroderma overlap syndrome-associated autoantigen
  • p2
  • p3
  • p4
  • PM/Scl-100Autoantigen PM/Scl 2
  • PM-Scl
  • PMSCL2PMSCL
  • polymyositis/scleroderma autoantigen 2 (100kD)
  • Polymyositis/scleroderma autoantigen 2
  • polymyositis/scleroderma autoantigen 2, 100kDa
  • RRP6
  • Rrp6p
  • RRP6Polymyositis/scleroderma autoantigen 100 kDa

Background

Part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions. Required for the 3'processing of the 7S pre-RNA to the mature 5.8S rRNA. Could be an exonuclease . Plays a role in replication-dependent histone mRNA degradation. Mediates the association of MTR4, C1D and MPP6 wth the exosome and this complex is required for the maturation of 5.8S rRNA. Required for nucleolar localization of C1D

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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RRP4 Antibody
NBP1-92355
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Western Blot RRP4 Antibody
Species: Hu, Mu, Rt
Applications: IHC, IHC-P, WB

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Bioinformatics

Gene Symbol EXOSC10