Western Blot: ER beta/NR3A2 Antibody (7B10.7) [NBP1-41194] - Non-transfected (-) and transfected (+) 293T whole cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Estrogen Receptor ...read more
ChIP usage reported in scientific literature. WB: Predicted MW is 59 kDa.
Theoretical MW
59 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publications using NBP1-41194 in the following applications:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
No Preservative
Purity
Protein G purified
Alternate Names for ER beta/NR3A2 Antibody (7B10.7)
ER beta
Erb
ER-beta
ESR2
ESR-BETA
ESTRB
estrogen receptor 2 (ER beta)
estrogen receptor beta 4
estrogen receptor beta
NR3A2
NR3A2ESRB
Nuclear receptor subfamily 3 group A member 2
Background
The human ER-beta is a newly discovered estrogen receptor initially cloned and characterized from testis. The size and structure of ER-beta is very similar to ER-alpha with the ligand and DNA binding domains being highly conserved, while the amino terminus which serves as their transactivation domain has diverged significantly. Similar in function to ER-alpha ER-beta binds to estrogen with a high affinity and regulates estrogen specific gene activation through direct interaction with estrogen response elements (ERE's).
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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