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DLL3 Antibody (rovalpituzumab) - Humanized

Images

 
Immobilized human DLL3 His at 2 ug/mL can bind DLL3 Antibody (rovalpituzumab) - Humanized, EC50=0.01407 ug/mL.
Human DLL3 HEK293 cells were stained with DLL3 Antibody (rovalpituzumab) - Humanized and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.01586 ug/mL.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, Func
Clone
rovalpituzumab
Clonality
Monoclonal
Host
Human
Conjugate
Unconjugated
Concentration
LYOPH

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DLL3 Antibody (rovalpituzumab) - Humanized Summary

Description
Expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Also known as 'rovalpituzumab'.

Upon receipt, store immediately at -20C or lower for 24 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
Additional Information
Recombinant Monoclonal Antibody
Immunogen
DLL3
Isotype
IgG1
Clonality
Monoclonal
Host
Human
Gene
DLL3
Purity
Protein A purified
Endotoxin Note
< 0.001EU/ug,determined by LAL method.
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Functional

Packaging, Storage & Formulations

Storage
Store at -20C in powder form. Store at -80C once reconstituted.
Buffer
Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A purified
Reconstitution Instructions
Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Alternate Names for DLL3 Antibody (rovalpituzumab) - Humanized

  • delta (Drosophila)-like 3
  • Delta3
  • delta-like 3 (Drosophila)
  • delta-like protein 3
  • DLL3
  • Drosophila Delta homolog 3
  • Pudgy
  • SCDO1
  • SCDO1delta3

Background

The DLL3 gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostos

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol DLL3
Uniprot