Dishevelled-1 Antibody

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

DVL-1 (Dishevelled-1) is a cytoplasmic phosphoprotein that is one of the three human orthologs of the Drosophila dishevelled segment polarity protein. Human DVL-1 is expressed in multiple tissues where it participates in Wnt signal transduction. DVL-1 is a modular protein containing DIX, PDZ and DEP linker regions that connect Wnt/Frizzled engagement to proteins involved in the inactivation of beta -catenin destruction in the Wnt canonical pathway. Human DVL-1 shows 93% aa identity with mouse and rat DVL-1 over the sequence used for immunization. Three shorter isoforms have been described, but it is unclear whether these are actually expressed.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: IHC-P.

Showing Publication 1 - 1 of 1.

Publication using AF3316	Applications	Species
Laumanns IP, Fink L, Wilhelm J, Wolff JC, Mitnacht-Kraus R, Graef-Hoechst S, Stein MM, Bohle RM, Klepetko W, Hoda MA, Schermuly RT, Grimminger F, Seeger W, Voswinckel R The noncanonical WNT pathway is operative in idiopathic pulmonary arterial hypertension. Am. J. Respir. Cell Mol. Biol., 2008-11-21;40(6):683-91. 2008-11-21 [PMID: 19029018] (IHC-P, Human)	IHC-P	Human

Array AF3316

• Dishevelled-1 Antibodies
• Dishevelled-1 Lysates
• Dishevelled-1 Proteins