Desmocollin-2 Antibody (003) [PerCP]

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Product Details

Summary
Reactivity RtSpecies Glossary
Applications IHC
Clone
003
Clonality
Monoclonal
Host
Rabbit
Conjugate
PerCP

Order Details

Desmocollin-2 Antibody (003) [PerCP] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
This antibody was obtained from a rabbit immunized with purified, recombinant Rat Desmocollin-2 (Uniprot#: Q3T1K6; Met1-Pro694).
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
DSC2
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Alternate Names for Desmocollin-2 Antibody (003) [PerCP]

  • ARVD11
  • Cadherin family member 2
  • CDHF2
  • CDHF2DGII/III
  • desmocollin 2
  • Desmocollin2
  • Desmocollin-2
  • Desmocollin-3
  • Desmosomal glycoprotein II
  • desmosomal glycoprotein II/III
  • Desmosomal glycoprotein III
  • DG2
  • DSC2
  • DSC3DKFZp686I11137

Background

Desmocollin 2 is encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11. Alternative splicing results in two transcript variants encoding distinct isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Bioinformatics

Gene Symbol DSC2