Novus Biologicals products are now on bio-techne.com

Cytokeratin, HMW Antibody (rKRTH/6617) [Janelia Fluor® 646]

Images

 
There are currently no images for Cytokeratin, HMW Antibody (NBP3-08675JF646).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
rKRTH/6617
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

Cytokeratin, HMW Antibody (rKRTH/6617) [Janelia Fluor® 646] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Synthetic peptide corresponding to Cytokeratin, HMW residues within aa300-400 of Cytokeratin, HMW (Uniprot: Q01546)
Localization
Cytoplasmic
Marker
Epithelial Marker
Specificity
The keratins are the typical intermediate filament proteins of epithelia, showing an outstanding degree of molecular diversity. Heteropolymeric filaments are formed by pairing of type I and type II molecules. In humans 54 functional keratin genes exist. They are expressed in highly specific patterns related to the epithelial type and stage of cellular differentiation. This antibody can detect high molecular weight CK1, CK2, CK3, CK4, CK5, CK6, CK7 and CK8. It is usually used in a cytokeratin cocktail with type I cytokeratins antibody.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
KRT76
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Cytokeratin, HMW Antibody (rKRTH/6617) [Janelia Fluor® 646]

  • CK-2P
  • cytokeratin 2
  • Cytokeratin-2P
  • HUMCYT2A
  • K2P
  • K76
  • keratin 76
  • keratin, type II cytoskeletal 2 oral
  • keratin-76
  • KRT2Bcytokeratin-2P
  • KRT2Pkeratin 2p
  • KRT76
  • Type-II keratin Kb9

Background

KRT76, also known as Keratin, type II cytoskeletal 2 oral, is a 638 amino acid that is approx. 66 kDa, belongs to the intermediate filament family responsible for the structural integrity of epithelial cells, subdivided into epithelial keratins and hair keratins, and probably contributes to terminal cornification. Studies are being performed in relation to this protein and obstructive jaundice, pharyngitis, jaundice, cervical cancer, neuronitis, colorectal cancer, cervicitis, interferon and hepatitis. This protein has been shown to have interactions with ATG13, PDPK1, ULK2, GABARAP, and PRKAA1 in cytoskeleton organization pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP2-42202
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, WB
NB110-41535
Species: Bv, Hu, Mu
Applications: ICC/IF (-), IHC (-), WB
NBP2-84109
Species: Hu
Applications: IHC, IHC-P, WB
H00054207-M03
Species: Hu
Applications: ELISA, WB
NBP1-77097
Species: Hu, Mu, Rt
Applications: ELISA, ICC/IF, IHC, IHC-P, WB
NBP2-32432
Species: Hu
Applications: ICC/IF, IHC, IHC-P
DTPA00
Species: Hu
Applications: ELISA
MAB1225
Species: Hu
Applications: Block, CyTOF-reported, Flow
NBP1-58906
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-Fr, IHC-P, WB
NBP2-41301
Species: Hu, Mu, Rt
Applications: ELISA, ICC/IF, IHC, IHC-P, WB
NB600-930
Species: Hu, Rt
Applications: ELISA, WB
NBP1-32728
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, IP, WB
NBP1-80271
Species: Hu, Mu
Applications: IHC, IHC-P, WB
DTM100
Species: Hu
Applications: ELISA
NBP1-20149
Species: Hu, Mu, Rt
Applications: IHC, IHC-Fr, IHC-P, WB
NB200-106
Species: Mu, Rt
Applications: ELISA, ICC/IF, IHC, IHC-Fr, IHC-P, WB
NBP3-08675JF646
Species: Hu
Applications: IHC

Publications for Cytokeratin, HMW Antibody (NBP3-08675JF646) (0)

There are no publications for Cytokeratin, HMW Antibody (NBP3-08675JF646).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Cytokeratin, HMW Antibody (NBP3-08675JF646) (0)

There are no reviews for Cytokeratin, HMW Antibody (NBP3-08675JF646). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for Cytokeratin, HMW Antibody (NBP3-08675JF646) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.
mFluor Violet Conjugated Antibodies

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Cytokeratin, HMW Antibody (rKRTH/6617) [Janelia Fluor® 646] and receive a gift card or discount.

Bioinformatics

Gene Symbol KRT76