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CRM1 Antibody [CoraFluor™ 1]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IP, WB (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-79811AF350
Alexa Fluor 405
NB100-79811AF405
Alexa Fluor 488
NB100-79811AF488
Alexa Fluor 532
NB100-79811AF532
Alexa Fluor 594
NB100-79811AF594
Alexa Fluor 647
NB100-79811AF647
Alexa Fluor 700
NB100-79811AF700
Alexa Fluor 750
NB100-79811AF750
Allophycocyanin
NB100-79811APC
Biotin
NB100-79811B
DyLight 350
NB100-79811UV
DyLight 405
NB100-79811V
DyLight 488
NB100-79811G
DyLight 550
NB100-79811R
DyLight 594
NB100-79811DL594
DyLight 650
NB100-79811C
DyLight 680
NB100-79811FR
DyLight 755
NB100-79811IR
FITC
NB100-79811F
HRP
NB100-79811H
Janelia Fluor 525
NB100-79811JF525
Janelia Fluor 549
NB100-79811JF549
Janelia Fluor 646
NB100-79811JF646
Janelia Fluor 669
NB100-79811JF669
PE
NB100-79811PE
PerCP
NB100-79811PCP
Unconjugated
NB100-79811
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CRM1 Antibody [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
The immunogen recognized by this antibody maps to a region between residues 375 and 425 of human Chromosome Region Maintenance 1 (Exportin 1) using the numbering given in entry NP_003391.1 (GeneID 7514).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
XPO1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunoprecipitation
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Immunogen affinity purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for CRM1 Antibody [CoraFluor™ 1]

  • Chromosome region maintenance 1 protein homolog
  • DKFZp686B1823
  • emb
  • exp1
  • exportin 1 (CRM1 homolog, yeast)
  • exportin 1 (CRM1, yeast, homolog)
  • Exportin-1 (required for chromosome region maintenance)
  • exportin-1
  • yeast, homolog

Background

Official Gene Symbol: XPO1 Gen Bank Accession Number: NP_003391 Gene ID: 7514 (human) Gene Map Locus: 2p16 (human) Nuclear transport receptors of karyopherin/importin-beta superfamily mediate various transport pathways between nucleus and cytoplasm. Exportin-1, a human homolog of yeast CRM1, is a novel karyopherin export receptor that mediates leucine-rich NES-dependent protein export. It interacts with RanGTP through its Ran-binding domain and also with nucleoporins including Nup214, Nup50, Nup42 and Nup159 during the process of exporting NES-containing proteins. It mediates the export of many cellular and viral proteins and ribonucleoproteins including HIV Rev Protein, ERK3, PKI, IRF-5, Cyclin-B, MAPKK, MAPKAP kinase 2, Snurportin, Cap-binding protein, and certain U snRNAs. Reports suggest exportin-1 also has a role in the regulation of NFAT and AP-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Species: Hu, Mu, Rt, Xp(-), Ye
Applications: CyTOF-ready, ELISA, Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
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(1D4B6) - BSA Free
NBP2-52553
ELISA RhoF Antibody (1D4B6) - BSA Free
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Species: Hu
Applications: CyTOF-ready, ELISA, Flow, WB
RNF34 Antibody
NBP2-56413
Western Blot RNF34 Antibody
Immunocytochemistry/ Immunofluorescence RNF34 Antibody
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Species: Hu
Applications: ICC/IF, IP, WB

CSE1L/CAS/Exportin-2 A
H00001434-M08
Western Blot CSE1L/CAS/Exportin-2 Antibody (3D8)
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(1 Review)
(11 Publications)
Species: Hu, Mu
Applications: ELISA, ICC/IF, IHC, IHC-P, WB
RanBP1 Antibody
NB100-79814
Western Blot RanBP1 Antibody
Western Blot RanBP1 Antibody
(2 Reviews)
(3 Publications)
Species: Hu, Mu
Applications: IHC, IHC-P, IP, WB
NUP214 Antibody
NB100-2244
Western Blot NUP214 Antibody
Immunohistochemistry-Paraffin NUP214 Antibody
Immunohistochemistry-Paraffin NUP214 Antibody
(1 Publication)
Species: Hu
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NXF1 Antibody
NBP1-31649
Immunohistochemistry-Paraffin NXF1 Antibody
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Species: Hu
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Antibody (WA-1)
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(24 Publications)
Species: Pm, Hu, Pm, Mu
Applications: Flow, ICC/IF, IHC, IHC-P, WB
SNURPORTIN1
Antibody
NBP1-31101
Immunohistochemistry-Paraffin SNURPORTIN1 Antibody
Western Blot SNURPORTIN1 Antibody
Immunocytochemistry/ Immunofluorescence SNURPORTIN1 Antibody
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
Exportin-5
Antibody (2C5-1B3)
H00057510-M01
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Immunoprecipitation Exportin-5 Antibody (2C5-1B3)
Sandwich ELISA Exportin-5 Antibody (2C5-1B3)
(3 Publications)
Species: Hu
Applications: ELISA, ICC/IF, IP, S-ELISA, WB
CRM1 Antibody
[CoraFluor™ 1]
NB100-79811CL1
CRM1 Antibody [CoraFluor™ 1]
Species: Hu
Applications: IP, WB (-)

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol XPO1