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Common gamma Chain/IL-2 R gamma Antibody (644346) [PE/Cy5.5]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
644346
Clonality
Monoclonal
Host
Rat
Conjugate
PE/Cy5.5

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB7842U-100UG
Alexa Fluor 405
FAB7842V-100UG
Alexa Fluor 488
FAB7842G-100UG
Alexa Fluor 532
FAB7842X
Alexa Fluor 594
FAB7842T-100UG
Alexa Fluor 647
FAB7842R-100UG
Alexa Fluor 700
FAB7842N-100UG
Alexa Fluor 750
FAB7842S-100UG
Allophycocyanin/Cy7
FAB7842APCCY7
Biotin
FAB7842B
CoraFluor 1
FAB7842CL1
DyLight 350
FAB7842D
DyLight 405
FAB7842E
DyLight 488
FAB7842K
DyLight 550
FAB7842L
DyLight 594
FAB7842M
DyLight 650
FAB7842W
DyLight 680
FAB7842Y
DyLight 755
FAB7842Z
HRP
FAB7842H
Janelia Fluor 525
FAB7842JF525
Janelia Fluor 549
FAB7842I
Janelia Fluor 646
FAB7842J
Janelia Fluor 669
FAB7842JF669
PE/Atto594
FAB7842PEATT594
PE/Cy7
FAB7842PECY7
PerCP
FAB7842C
Unconjugated
MAB7842
mFluor Violet 450 SE
FAB7842MFV450
mFluor Violet 500 SE
FAB7842MFV500
mFluor Violet 610 SE
FAB7842MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB7842
Carrier Free
MAB7842
Carrier Free
MAB7842-SP
Carrier Free
FAB7842V-100UG
Carrier Free
FAB7842U-100UG
Carrier Free
FAB7842T-100UG
Carrier Free
FAB7842S-100UG
Carrier Free
FAB7842R-100UG
Carrier Free
FAB7842N-100UG
Carrier Free
FAB7842G-100UG
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Common gamma Chain/IL-2 R gamma Antibody (644346) [PE/Cy5.5] Summary

Immunogen
S. frugiperda insect ovarian cell line Sf21-derived recombinant mouse Common gamma Chain/IL-2 R gamma
Trp23-Ala263 (predicted)
Accession # P34902
Specificity
Detects mouse Common gamma Chain/IL-2 R gamma in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse (rm) IL-2 R alpha , rmIL‑2 R beta , recombinant human (rh) IL-2 R gamma , rhIL-15 R alpha , recombinant rat IL-2 R alpha , or recombinant canine IL-2 R alpha is observed.
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
IL2RG
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for Common gamma Chain/IL-2 R gamma Antibody (644346) [PE/Cy5.5]

  • CD132 antigen
  • CD132
  • CIDX
  • combined immunodeficiency, X-linked
  • common cytokine receptor gamma chain
  • Common gamma Chain
  • common gamma-chain
  • cytokine receptor common subunit gamma
  • gamma(c)
  • IL-2 R gamma
  • IL-2 receptor subunit gamma
  • IL2R gamma
  • IL-2R subunit gamma
  • IL2RG
  • IL-2RG
  • IMD4
  • interleukin 2 receptor, gamma
  • Interleukin-2 receptor subunit gamma
  • P64
  • SCIDX
  • SCIDX1
  • severe combined immunodeficiency

Background

The interleukin 2 (IL2) receptor gamma chain (IL2RG), an important signalling component of many interleukin receptors(IL2,IL4,IL7,IL9, and IL15), is thus referred to as the common gamma chain. Mutations in this X-chromosome-linked genecause X-linked severe combined immunodeficiency (XSCID). (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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As an alternative, please consider our next generation Recombinant Human IL-2 (BT-002). It has equivalent bioactivity to Recombinant Human IL-2 (Catalog # 202-IL). It combines R&D Systems quality with scalability that allows for a solid supply chain. Both Recombinant Human IL-2 proteins are measured in a cell proliferation assay using CTLL 2 mouse cytotoxic T cells.
IL-2 [Unconjugated]
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Bioinformatics

Gene Symbol IL2RG