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COG2 Antibody (4C8)

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Western Blot: COG2 Antibody (4C8) [H00022796-M09] - Analysis of COG2 expression in transfected 293T cell line by COG2 monoclonal antibody (M09), clone 4C8. Lane 1: COG2 transfected lysatE (83.2 KDa). Lane 2: Non-transfected lysate.
Western Blot: COG2 Antibody (4C8) [H00022796-M09] - Analysis of COG2 expression in transfected 293T cell line by COG2 monoclonal antibody (M09), clone 4C8. Lane 1: COG2 transfected lysatE (83.2 KDa). Lane 2: ...read more
Western Blot: COG2 Antibody (4C8) [H00022796-M09] - Western blot analysis of COG2 over-expressed 293 cell line, cotransfected with COG2 Validated Chimera RNAi or non-transfected control. Blot probed with H00022796-M09. ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, KD
Clone
4C8
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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COG2 Antibody (4C8) Summary

Immunogen
COG2 (NP_031383, 639 a.a. ~ 738 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. LSESTHKYYETVSDVLNSVKKMEESLKRLKQARKTTPANPVGPSGGMSDDDKIRLQLALDVEYLGEQIQKLGLQASDIKSFSALAELVAAAKDQATAEQP
Specificity
COG2 (4C8)
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
COG2
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Knockdown Validated
  • Western Blot 1:500RNAi Validation
Application Notes
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control. It has also been used for RNAi validation.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for COG2 Antibody (4C8)

  • component of oligomeric golgi complex 2COG complex subunit 2
  • conserved oligomeric Golgi complex protein 2
  • conserved oligomeric Golgi complex subunit 2
  • LDLCbrefeldin A-sensitive, peripheral Golgi protein
  • low density lipoprotein receptor defect C complementing
  • Low density lipoprotein receptor defect C-complementing protein

Background

Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG2 (Ungar et al., 2002 [PubMed 11980916]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol COG2
Entrez
OMIM
Uniprot