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cGK2/PRKG2 Antibody

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

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cGK2/PRKG2 Antibody Summary

Immunogen
Immunized with recombinant Human cGK2/PRKG2 (Uniprot#: Q13237; Leu453-Leu728 (Uniprot#: Q13237)
Clonality
Polyclonal
Host
Rabbit
Gene
PRKG2
Purity
Antigen and protein A Affinity-purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 5-20ug/mL
  • Immunohistochemistry 5-20ug/mL
  • Western Blot 0.5-2ug/mL

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.01M PBS, pH7.4, 50% glycerol
Preservative
0.05% Proclin 300
Concentration
0.5 mg/ml
Purity
Antigen and protein A Affinity-purified

Alternate Names for cGK2/PRKG2 Antibody

  • cGK 2
  • cGK2
  • cGK2/PRKG2
  • cGKII
  • cGKIIcGK2
  • cGMP-dependent protein kinase 2
  • cGMP-dependent protein kinase II
  • EC 2.7.11
  • PRKG2
  • PRKGR2
  • PRKGR2EC 2.7.11.12
  • protein kinase, cGMP-dependent, type II

Background

cGK2/PRKG2, also known as cGMP-dependent protein kinase 2, is 762 amino acids long and approximately 87kDa. cGK2/PRKG2 is a protein kinase that is highly expressed in the brain, intestine and lung. Current research surrounding cGK2/PRKG2 has shown a potential link with several disorders and diseases including cystic fibrosis, gout, malaria, lung cancer, alcoholism, diarrhea, and hyperphenylalaninemia. cGK2/PRKG2 may also interact with PTS, LASP1, YWHAB, MYLK, and PLCB3 in pathways such as cGMP signaling, platelet homeostasis, EDNRB signaling, signaling in gap junctions, nitric oxide metabolism, and eNOS activation and regulation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PRKG2