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Cdc6 Antibody (cdc6 9H8/5) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity YeSpecies Glossary
Applications WB, IHC, IP
Clone
cdc6 9H8/5
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

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Cdc6 Antibody (cdc6 9H8/5) [Janelia Fluor® 646] Summary

Immunogen
Cdc6 from S. cerevisiae.
Localization
Plasma membrane
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CDC6
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Saccharomyces cerevisiae

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Cdc6 Antibody (cdc6 9H8/5) [Janelia Fluor® 646]

  • CDC18LHsCDC18
  • Cdc18-related protein
  • CDC6 (cell division cycle 6, S. cerevisiae) homolog
  • CDC6 cell division cycle 6 homolog (S. cerevisiae)
  • CDC6 cell division cycle 6 homolog
  • CDC6-related protein
  • cell division control protein 6 homolog
  • cell division cycle 6 homolog (S. cerevisiae)
  • cell division cycle 6 protein
  • HsCdc18
  • HsCDC6
  • p62(cdc6)

Background

Cdc6 is encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Array NB100-2684JF646

Research Areas for Cdc6 Antibody (NB100-2684JF646)

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Bioinformatics

Gene Symbol CDC6