Independent Antibodies: Immunohistochemistry-Paraffin: BAIAP2 Antibody [NBP1-88711] - Staining of human cerebellum, cerebral cortex, fallopian tube and prostate using Anti-BAIAP2 antibody NBP1-88711 (A) shows ...read more
Western Blot: BAIAP2 Antibody [NBP1-88711] - Analysis in rat cell line NBT-II.
Immunocytochemistry/ Immunofluorescence: BAIAP2 Antibody [NBP1-88711] - Staining of human cell line U-2 OS shows localization to plasma membrane & cytosol. Antibody staining is shown in green.
Western Blot: BAIAP2 Antibody [NBP1-88711] - Analysis in human cell line A-431.
Immunohistochemistry-Paraffin: BAIAP2 Antibody [NBP1-88711] - Staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.
Immunohistochemistry-Paraffin: BAIAP2 Antibody [NBP1-88711] - Staining of human cerebral cortex shows strong cytoplasmic positivity in neurons.
Immunohistochemistry-Paraffin: BAIAP2 Antibody [NBP1-88711] - Staining of human fallopian tube shows moderate to strong cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: BAIAP2 Antibody [NBP1-88711] - Staining of human prostate shows moderate to strong cytoplasmic and membranous positivity in glandular cells.
This antibody was developed against Recombinant Protein corresponding to amino acids: WFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPAQTASGFKQRPYSVAVPAFSQGLDDYGARSMSRNP
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BAIAP2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Use in Mouse reported in scientific literature (PMID:31483294).
Packaging, Storage & Formulations
Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified
Alternate Names for BAIAP2 Antibody
BAI1-associated protein 2IRS-58
BAI-associated protein 2
BAP2
brain-specific angiogenesis inhibitor 1-associated protein 2
Fas ligand-associated factor 3
FLAF3
Insulin receptor substrate p53
Insulin receptor substrate p53/p58
Insulin receptor substrate protein of 53 kDa
IRSP53
IRSp53/58
Protein BAP2
Background
BAIAP2 is encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This interaction at the cytoplasmic membrane is crucial to the function of this protein, which may be involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. Alternative splicing of the 3'-end of this gene results in three products of undetermined function.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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