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Aminomethyltransferase Antibody (OTI6F4) [Janelia Fluor® 525]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clone
OTI6F4
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 525

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-70171AF350
Alexa Fluor 405
NBP2-70171AF405
Alexa Fluor 488
NBP2-70171AF488
Alexa Fluor 532
NBP2-70171AF532
Alexa Fluor 594
NBP2-70171AF594
Alexa Fluor 647
NBP2-70171AF647
Alexa Fluor 700
NBP2-70171AF700
Alexa Fluor 750
NBP2-70171AF750
Allophycocyanin
NBP2-70171APC
Biotin
NBP2-70171B
CoraFluor 1
NBP2-70171CL1
DyLight 350
NBP2-70171UV
DyLight 405
NBP2-70171V
DyLight 488
NBP2-70171G
DyLight 550
NBP2-70171R
DyLight 594
NBP2-70171DL594
DyLight 650
NBP2-70171C
DyLight 680
NBP2-70171FR
DyLight 755
NBP2-70171IR
FITC
NBP2-70171F
HRP
NBP2-70171H
Janelia Fluor 549
NBP2-70171JF549
Janelia Fluor 585
NBP2-70171JF585
Janelia Fluor 635
NBP2-70171JF635
Janelia Fluor 646
NBP2-70171JF646
Janelia Fluor 669
NBP2-70171JF669
PE
NBP2-70171PE
PerCP
NBP2-70171PCP
Unconjugated
NBP2-46516
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-46516
Azide and BSA Free
NBP2-70171
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Aminomethyltransferase Antibody (OTI6F4) [Janelia Fluor® 525] Summary

Immunogen
Human recombinant protein fragment corresponding to amino acids 146-403 of human AMT(NP_000472) produced in E.coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
AMT
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Aminomethyltransferase Antibody (OTI6F4) [Janelia Fluor® 525]

  • aminomethyltransferase
  • EC 2.1.2.10
  • GCE
  • GCSTaminomethyltransferase (glycine cleavage system protein T)
  • glycine cleavage system protein T
  • NKHmitochondrial

Background

The enzyme system for cleavage of glycine (glycine cleavage system; EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase; MIM 238300), H protein (a lipoic acid-containing protein; MIM 238330), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase; MIM 238331). Glycine encephalopathy (GCE; MIM 605899) may be due to a defect in any one of these enzymes.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol AMT