alpha-2A Adrenergic R/ADRA2A Antibody Summary
Immunogen |
Peptide with sequence C-TERRPNGLGPERS corresponding to internal region according to NP_000672.2. |
Predicted Species |
Rat (100%), Canine (100%). Backed by our 100% Guarantee. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Goat |
Gene |
ADRA2A |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Flow Cytometry 10 ug/mL
- Immunocytochemistry/ Immunofluorescence 10 ug/mL
- Peptide ELISA Detection limit 1:32000
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Control |
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Publications |
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Packaging, Storage & Formulations
Storage |
Store at -20C. Avoid freeze-thaw cycles. |
Buffer |
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA |
Preservative |
0.02% Sodium Azide |
Concentration |
0.5 mg/ml |
Purity |
Immunogen affinity purified |
Alternate Names for alpha-2A Adrenergic R/ADRA2A Antibody
Background
This study investigates the involvement of alpha2-adrenergic receptors (AR) in mouse brain induced by a low dose of methamphetamine (METH, 2 mg/kg). Immunohistochemical studies show that alpha2A-AR increased in the dentate gyrus area of the hippocampus 24 h after five repeated administrations of METH. The hippocampal alpha2A-AR proteins rose 3.2-fold when compared to the saline-administered mice. The other adrenergic receptor, alpha1D-AR, were not changed by the treatment. Moreover, alphao-subunits of GTP-binding proteins (Galphao), one of the downstream molecules of alpha2A-AR, was also increased by the treatment. These suggest that the repeated administration of low-doses of METH causes quantitative changes of the signaling of alpha2A-AR in the mouse hippocampus.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for alpha-2A Adrenergic R/ADRA2A Antibody (NB100-2819)(2)
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FAQs for alpha-2A Adrenergic R/ADRA2A Antibody (NB100-2819) (0)
Control Lysate(s)
Secondary Antibodies
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Isotype Controls
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