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alpha-2A Adrenergic R/ADRA2A Antibody

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Immunocytochemistry/ Immunofluorescence: alpha-2A Adrenergic R/ADRA2A Antibody [NB100-2819] - Analysis of paraformaldehyde fixed MCF7 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/mL) followed by ...read more
Flow Cytometry: alpha-2A Adrenergic R/ADRA2A Antibody [NB100-2819] - Analysis of paraformaldehyde fixed MCF7 cells (blue line), permeabilized with 0.5% Triton. Primary incubation overnight (10 ug/mL) followed by Alexa ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, CaSpecies Glossary
Applications ELISA, Flow, ICC/IF
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

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alpha-2A Adrenergic R/ADRA2A Antibody Summary

Immunogen
Peptide with sequence C-TERRPNGLGPERS corresponding to internal region according to NP_000672.2.
Predicted Species
Rat (100%), Canine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
ADRA2A
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 ug/mL
  • Immunocytochemistry/ Immunofluorescence 10 ug/mL
  • Peptide ELISA Detection limit 1:32000
Control
alpha-2A Adrenergic R/ADRA2A Overexpression Lysate
Publications
Read Publications using NB100-2819.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for alpha-2A Adrenergic R/ADRA2A Antibody

  • a-2A AdrenergicR
  • ADRA2
  • ADRA2A
  • ADRA2Ralpha-2-adrenergic receptor, platelet type
  • ADRARZNF32
  • adrenergic, alpha-2A-, receptor
  • Alpha-2 adrenergic receptor subtype C10
  • alpha-2A Adrenergic R
  • alpha-2A adrenergic receptor
  • alpha2A AdrenergicR
  • Alpha-2A adrenoceptor
  • Alpha-2A adrenoreceptor
  • alpha-2AAR subtype C10
  • ALPHA2AAR
  • Alpha-2AAR
  • ZNF32

Background

This study investigates the involvement of alpha2-adrenergic receptors (AR) in mouse brain induced by a low dose of methamphetamine (METH, 2 mg/kg). Immunohistochemical studies show that alpha2A-AR increased in the dentate gyrus area of the hippocampus 24 h after five repeated administrations of METH. The hippocampal alpha2A-AR proteins rose 3.2-fold when compared to the saline-administered mice. The other adrenergic receptor, alpha1D-AR, were not changed by the treatment. Moreover, alphao-subunits of GTP-binding proteins (Galphao), one of the downstream molecules of alpha2A-AR, was also increased by the treatment. These suggest that the repeated administration of low-doses of METH causes quantitative changes of the signaling of alpha2A-AR in the mouse hippocampus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for alpha-2A Adrenergic R/ADRA2A Antibody (NB100-2819)(2)

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for alpha-2A Adrenergic R/ADRA2A Antibody (NB100-2819) (0)

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ADRA2A
Entrez
Uniprot