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alpha-2A Adrenergic R/ADRA2A Antibody (1006614) [mFluor Violet 610 SE]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
1006614
Clonality
Monoclonal
Host
Mouse
Conjugate
mFluor Violet 610 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB10129U-100UG
Alexa Fluor 405
FAB10129V-100UG
Alexa Fluor 488
FAB10129G-100UG
Alexa Fluor 532
FAB10129X
Alexa Fluor 594
FAB10129T-100UG
Alexa Fluor 647
FAB10129R-100UG
Alexa Fluor 700
FAB10129N-100UG
Alexa Fluor 750
FAB10129S-100UG
Allophycocyanin
FAB10129A
Allophycocyanin/Cy7
FAB10129APCCY7
Biotin
FAB10129B
CoraFluor 1
FAB10129CL1
DyLight 350
FAB10129D
DyLight 405
FAB10129E
DyLight 488
FAB10129K
DyLight 550
FAB10129L
DyLight 594
FAB10129M
DyLight 650
FAB10129W
DyLight 680
FAB10129Y
DyLight 755
FAB10129Z
FITC
FAB10129F
HRP
FAB10129H
Janelia Fluor 525
FAB10129JF525
Janelia Fluor 549
FAB10129I
Janelia Fluor 646
FAB10129J
Janelia Fluor 669
FAB10129JF669
PE
FAB10129P
PE/Atto594
FAB10129PEATT594
PE/Cy5.5
FAB10129PECY55
PE/Cy7
FAB10129PECY7
PerCP
FAB10129C
Unconjugated
MAB10129-100
mFluor Violet 450 SE
FAB10129MFV450
mFluor Violet 500 SE
FAB10129MFV500
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB10129-100
Carrier Free
MAB10129-100
Carrier Free
MAB10129-SP
Carrier Free
FAB10129V-100UG
Carrier Free
FAB10129U-100UG
Carrier Free
FAB10129T-100UG
Carrier Free
FAB10129S-100UG
Carrier Free
FAB10129R-100UG
Carrier Free
FAB10129N-100UG
Carrier Free
FAB10129G-100UG
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alpha-2A Adrenergic R/ADRA2A Antibody (1006614) [mFluor Violet 610 SE] Summary

Immunogen
Synthetic peptide containing Human alpha ‑2A Adrenergic R/ADRA2A
Specificity
Detects human alpha ‑2A Adrenergic R/ADRA2A in direct ELISAs.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for alpha-2A Adrenergic R/ADRA2A Antibody (1006614) [mFluor Violet 610 SE]

  • a-2A AdrenergicR
  • ADRA2
  • ADRA2A
  • ADRA2Ralpha-2-adrenergic receptor, platelet type
  • ADRARZNF32
  • adrenergic, alpha-2A-, receptor
  • Alpha-2 adrenergic receptor subtype C10
  • alpha-2A Adrenergic R
  • alpha-2A adrenergic receptor
  • alpha2A AdrenergicR
  • Alpha-2A adrenoceptor
  • Alpha-2A adrenoreceptor
  • alpha-2AAR subtype C10
  • ALPHA2AAR
  • Alpha-2AAR
  • ZNF32

Background

This study investigates the involvement of alpha2-adrenergic receptors (AR) in mouse brain induced by a low dose of methamphetamine (METH, 2 mg/kg). Immunohistochemical studies show that alpha2A-AR increased in the dentate gyrus area of the hippocampus 24 h after five repeated administrations of METH. The hippocampal alpha2A-AR proteins rose 3.2-fold when compared to the saline-administered mice. The other adrenergic receptor, alpha1D-AR, were not changed by the treatment. Moreover, alphao-subunits of GTP-binding proteins (Galphao), one of the downstream molecules of alpha2A-AR, was also increased by the treatment. These suggest that the repeated administration of low-doses of METH causes quantitative changes of the signaling of alpha2A-AR in the mouse hippocampus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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