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Adenylate Cyclase 8 Antibody (ADCY8/7573) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
ADCY8/7573
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

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Adenylate Cyclase 8 Antibody (ADCY8/7573) [Janelia Fluor® 646] Summary

Immunogen
Recombinant fragment (around aa1-200) of human Adenylate Cyclase 8 protein (exact sequence is proprietary)
Localization
Cell surface. Multi-pass membrane protein. Cytoplasm.
Isotype
IgG2 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
ADCY8
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Adenylate Cyclase 8 Antibody (ADCY8/7573) [Janelia Fluor® 646]

  • AC8
  • ADCY3
  • ADCY8
  • adenylate cyclase 8 (brain)
  • Adenylate Cyclase 8
  • adenylate cyclase type 8
  • Adenylate cyclase type VIII
  • Adenylyl cyclase 8
  • adenylyl cyclase-8, brain
  • ATP pyrophosphate-lyase 8
  • Ca(2+)/calmodulin-activated adenylyl cyclase
  • EC 4.6.1.1
  • HBAC1

Background

ADCY8, also known as Adenylate cyclase type 8, is a 140 kDa 1,251 amino acid protein, and is involved in the encoding of a membrane-bound enzyme that has to do with learning. This protein has also been shown to have interactions with CALM1, CALM2, CALM3, PPP2CA, and CFTR in the Signaling by FGFR, PKA activation in glucagon signaling, DAG and IP3 signaling, Regulation of Water Balance by Renal Aquaporins, and Opioid Signalling pathway. Disease research is currently being studied with relation to ADCY8 and drug dependence, bipolar disorder, cholera, and Alzheimer's disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ADCY8