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Cartilage Morphogenesis Pathway Bioinformatics

Disease and disorder research has been conducted in relation to the Cartilage Morphogenesis Pathway and Crest Syndrome, Hypertrophy, Craniofacial Abnormalities, Degenerative Polyarthritis, Dwarfism. The study of the Cartilage Morphogenesis Pathway has been mentioned in research publications which can be found using our bioinformatics tool below. The Cartilage Morphogenesis Pathway has been researched in relation to Cartilage Development, Chondrocyte Differentiation, Limb Development, Gastrulation, Cell Adhesion. The Cartilage Morphogenesis Pathway complements our catalog of research reagents including antibodies and ELISA kits against SS18L1, GDF5, EDN1, COL2A1, LECT1.

Top Research Reagents

We have 1286 products for the study of the Cartilage Morphogenesis Pathway that can be applied to Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

Ext2 Antibody
NBP1-58297
Western Blot: Ext2 Antibody [NBP1-58297] - Human Hela, Antibody Dilution: 1.0 ug/ml EXT2 is supported by BioGPS gene expression data to be expressed in HeLa.Immunohistochemistry: Ext2 Antibody [NBP1-58297] - Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Cytoplasmic Primary Antibody Concentration: N/A Other Working Concentrations: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

Collagen II Antibody (5B2.5) - BSA Free
NB600-844
Western Blot: Collagen II Antibody (5B2.5) [NB600-844] - Expression levels of related genes during differentiation induction in the 2D environment. Expression of ACAN, collagen II, collagen X and Runx2 was detected by western blotting on day 10 during induction. Image collected and cropped by Citeab from the following publication (Chondrogenic differentiation of bone marrow-derived mesenchymal stem cells following transfection with Indian hedgehog and sonic hedgehog using a rotary cell culture system. Cell Mol Biol Lett (2019)) licensed under a CC-BY license.Immunohistochemistry-Paraffin: Collagen II Antibody (5B2.5) [NB600-844] - Staining results for the process of differentiation induction in the RCCS environment. Collagen II immune-histochemical staining on cells after inoculation onto slides. Image collected and cropped by Citeab from the following publication (Chondrogenic differentiation of bone marrow-derived mesenchymal stem cells following transfection with Indian hedgehog and sonic hedgehog using a rotary cell culture system. Cell Mol Biol Lett (2019)) licensed under a CC-BY license.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

50 Publications
p57 Kip2 Antibody
NBP1-89917
Immunohistochemistry-Paraffin: p57 Kip2 Antibody [NBP1-89917] - Staining in human placenta and colon tissues using anti-CDKN1C antibody. Corresponding CDKN1C RNA-seq data are presented for the same tissues.Western Blot: p57 Kip2 Antibody [NBP1-89917] - Analysis in human placenta tissue.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

1 Publication
SS18L1 Antibody
NBP2-20486
Western Blot: SS18L1 Antibody [NBP2-20486] - Sample (50 ug of whole cell lysate) A: Mouse Brain, 10% SDS PAGE gel, diluted at 1:1000.Immunocytochemistry/Immunofluorescence: SS18L1 Antibody [NBP2-20486] - Immunofluorescence analysis of paraformaldehyde-fixed A431, using antibody at 1:500 dilution.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

Osteopontin/OPN Antibody [Unconjugated]
AF808
Osteopontin/OPN was detected in immersion fixed C2C12 mouse myoblast cell line (left panel, positive stain) and mouse splenocytes (right panel, negative stain) using Goat Anti-Mouse Osteopontin/OPN Antigen Affinity-purified Polyclonal Antibody (Catalog # AF808) at 5 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; <a class=Osteopontin/OPN was detected in perfusion fixed frozen sections of mouse thymus using Mouse Osteopontin/OPN Antigen Affinity-purified Polyclonal Antibody (Catalog # AF808) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; <a class=

Goat Polyclonal
Species Mouse
Applications WB, IHC, ELISA(Cap)

     2 Reviews

203 Publications
Frizzled-6 Antibody
AF1526
FZD6 protein polarity is lost in mutant tympanic ciliary epithelium.(A–B) The distribution of the core PCP protein, FZD6, was examined by immunofluorescence staining. Ciliated epithelial cells were marked with anti-acetylated-alpha -tubulin antibody (rose). (A1, A2) In the wild-type mice (at P25), FZD6 protein localized asymmetrically to the cell cortex at the level of the apical junctions (arrow in A2). (B1, B2) However, in the mutant mice (at P25), FZD6 protein lost its polarized distribution and was located on the entire membrane at the apical level (arrows in B2).(A3, B3) Schematic diagram of FZD6 protein (red line) distribution in wild-type and Spag6−/− mice. The color codes are the same as that in panel A1 and B1. Bars: A, 5 µm; B, 7.5 µm. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/25393619), licensed under a CC-BY license. Not internally tested by R&D Systems.FZD6 protein polarity is lost in mutant tympanic ciliary epithelium.(A–B) The distribution of the core PCP protein, FZD6, was examined by immunofluorescence staining. Ciliated epithelial cells were marked with anti-acetylated-alpha -tubulin antibody (rose). (A1, A2) In the wild-type mice (at P25), FZD6 protein localized asymmetrically to the cell cortex at the level of the apical junctions (arrow in A2). (B1, B2) However, in the mutant mice (at P25), FZD6 protein lost its polarized distribution and was located on the entire membrane at the apical level (arrows in B2).(A3, B3) Schematic diagram of FZD6 protein (red line) distribution in wild-type and Spag6−/− mice. The color codes are the same as that in panel A1 and B1. Bars: A, 5 µm; B, 7.5 µm. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/25393619), licensed under a CC-BY license. Not internally tested by R&D Systems.

Goat Polyclonal
Species Mouse
Applications WB, Flow, IHC

18 Publications
DAN/NBL1 Antibody [Unconjugated]
AF755

Goat Polyclonal
Species Mouse
Applications WB, Block

1 Publication
Indian Hedgehog/Ihh Antibody - N-Terminus
AF1705
Indian Hedgehog was detected in immersion fixed frozen sections of mouse embryo (15 d.p.c.) using Goat Anti-Mouse Indian Hedgehog N-Terminus Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1705) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # <a class=

Goat Polyclonal
Species Mouse
Applications WB, IHC

3 Publications
SOX9 Antibody [Unconjugated]
AF3075
Western blot shows lysates of HeLa human cervical epithelial carcinoma cell line, KATO-III human gastric carcinoma cell line, COLO 205 human colorectal adenocarcinoma cell line, and Hep3B human hepatocellular carcinoma cell line. PVDF membrane was probed with 0.5 µg/mL of Goat Anti-Human SOX9 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3075) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (<a class=SOX9 was detected in immersion fixed HEK293 human embryonic kidney cell line using 10 µg/mL Human SOX9 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3075) for 3 hours at room temperature. Cells were stained with the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; <a class=

Goat Polyclonal
Species Human
Applications WB, Simple Western, ICC

     2 Reviews

145 Publications
GDF-5/BMP-14 Antibody [Unconjugated]
AF853
GDF-5 was detected in immersion fixed frozen sections of mouse embyro (12 d.p.c.) using 15 µg/mL Goat Anti-Mouse GDF-5 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF853) overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; <a class=Western blot shows lysates of NIH‑3T3 mouse embryonic fibroblast cell line. PVDF membrane was probed with 1 µg/mL of Goat Anti-Mouse GDF‑5/BMP‑14 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF853) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # <a class=NoLineLink href=

Goat Polyclonal
Species Mouse
Applications WB, IHC

6 Publications
Chondromodulin-1/LECT1 Antibody (394002)
MAB41681

Mouse Monoclonal
Species Human
Applications WB

2 Publications
COMP/Thrombospondin-5 [HRP]
DCMP0
N/A COMP/Thrombospondin-5 [HRP]N/A COMP/Thrombospondin-5 [HRP]


Species Human
Applications ELISA

11 Publications
Endothelin-1 [HRP]
DET100
N/A Endothelin-1 [HRP]N/A Endothelin-1 [HRP]


Species Multi-Species
Applications ELISA

79 Publications
Noggin [Unconjugated]
6057-NG
Recombinant human Noggin (Catalog # 6057-NG) has a molecular weight (MW) of 58.9 kDa as analyzed by SEC-MALS, suggesting that this protein is a homodimer.  MW may differ from predicted MW due to post-translational modifications (PTMs) present (i.e. Glycosylation).BG01V human embryonic stem cells were cultured in Mouse Embryonic Fibroblast Conditioned Media supplemented with FGF basic (5 ng/mL). Stem cells were driven into early cells of the neuroectoderm using a 3 day incubation in recombinant human Noggin (25 µg/mL) from either R&D Systems (Lot 1, Lot 2; Catalog # 6057-NG) or from two separate competitors (Competitor 1, Competitor 2). Control cells were not incubated in Noggin (No Noggin). The cells were stained for the early ectoderm marker, Otx2, and the neuroectoderm marker, SOX1. (A) Representative images of SOX1 (green), Otx2 (red), and DAPI (blue) staining in embryonic stem cells differentiated with Noggin from R&D Systems or Noggin from Competitor 2. (B) SOX1+ clusters were quantified under each of the indicated culture conditions. Cells treated with R&D Systems Noggin showed an increase in SOX1+ cells compared to both untreated and competitor-treated cells. R&D Systems Noggin showed consistent differentiation across the lots tested. BG01V human embryonic stem cells are licensed from ViaCyte, Inc.


Species Human
Applications BA

197 Publications
R-Spondin 3 [Unconjugated]
3500-RS
Recombinant human R-Spondin 3 (Catalog # 3500-RS) has a molecular weight (MW) of 36.1 kDa as analyzed by SEC-MALS, suggesting that this protein is a monomer.  MW may differ from predicted MW due to post-translational modifications (PTMs) present (i.e. Glycosylation).Recombinant Human R-Spondin 3 (Catalog # 3500-RS), in the presence of Recombinant Mouse Wnt 3a (Catalog # 1324-WN; 5 ng/mL), induces activation of beta-catenin in HEK293T cells measured using the Topflash assay. The ED<sub>50</sub> for this effect is 0.50-2.00 ng/mL.


Species Human
Applications BA

17 Publications
CHST11 Antibody (4F1)
H00050515-M01
Western Blot: CHST11 Antibody (4F1) [H00050515-M01] - CHST11 monoclonal antibody (M01), clone 4F1 Analysis of CHST11 expression in K-562.Western Blot: CHST11 Antibody (4F1) [H00050515-M01] - Analysis of CHST11 expression in transfected 293T cell line by CHST11 monoclonal antibody (M01), clone 4F1.Lane 1: CHST11 transfected lysate (Predicted MW: 41.6 KDa).Lane 2: Non-transfected lysate.

Mouse Monoclonal
Species Human
Applications WB, ELISA, S-ELISA