Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, IHC
Host: Goat Polyclonal
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
PARP2 encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found.
Bioinformatics
Uniprot |
Human |
Product By Gene ID |
10038 |
Alternate Names |
- ADP-ribosyltransferase (NAD+; poly(ADP-ribose) polymerase)-like 2
- ADPRT-2
- ADPRT2pADPRT-2
- ADPRTL2EC 2.4.2.30
- ADPRTL3
- hPARP-2
- NAD(+) ADP-ribosyltransferase 2
- PARP-2
- poly (ADP-ribose) polymerase 2
- poly (ADP-ribose) polymerase family, member 2
- poly (ADP-ribosyl) transferase-like 2
- poly [ADP-ribose] polymerase 2
- poly(ADP-ribose) synthetase
- Poly[ADP-ribose] synthase 2
- poly[ADP-ribose] synthetase 2
|
Research Areas for PARP2
Find related products by research area and learn more about each of the different research areas below.
DNA RepairHypoxia