p21/CIP1/CDKN1A Products

Description

Cell cycle progression is regulated by cyclins and their cognate Cdks. p21 (WAF1/CIP1) inhibits the activity of each member of the cyclin/Cdk family, and over expression of this protein inhibits the proliferation of mammalian cells. The expression of p21 is inducible by a wide range of stress stimuli. p21 is tightly regulated at the transcriptional level by p53, and probably serves as the effector of p53 cell cycle control.

Bioinformatics

Uniprot	AAH00312 Human AAH00312.1 Human NP_000380 Human NP_000380.1 Human P38936 Human P39689 Mouse
Product By Gene ID	1026
Alternate Names	CAP20cyclin-dependent kinase inhibitor 1 CDK-interacting protein 1 CDKN1melanoma differentiation associated protein 6 CIP1WAF1CDK-interaction protein 1 cyclin-dependent kinase inhibitor 1A (p21, Cip1) MDA6 MDA-6 Melanoma differentiation-associated protein 6 p21 P21 p21CIP1 p21Cip1/Waf1 PIC1 SDI1DNA synthesis inhibitor wild-type p53-activated fragment 1

Research Areas for p21/CIP1/CDKN1A

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Breast Cancer
Cancer
Cell Cycle and Replication
DNA Repair
Phospho-Specific