MMP-13 Products

Description

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-12 (also designated macrophage metalloelastase) is produced in alveolar macrophages and degrades elastin. MMP-12 may contribute to elastin degradation occurring in granulomatous skin diseases and may also participate in macrophage migration through the epidermal and vascular basement membranes in inflammatory disorders.

Bioinformatics

Entrez	100008685 Rabbit 171052 Rat 17386 Mouse 281914 Bovine 4322 Human
Uniprot	NM_002427 Human NP_002418 Human NP_002418.1 Human P23097 Rat P45452 Human P45452 Human
Product By Gene ID	4322
Alternate Names	CLG 3 CLG3EC 3.4.24 collagenase 3 EC 3.4.24.- EC 3.4.24.22 EC 3.4.24.24 EC 3.4.24.35 EC 3.4.24.65 EC 3.4.24.7 MANDP1 matrix metallopeptidase 13 (collagenase 3) matrix metalloproteinase 13 (collagenase 3) Matrix metalloproteinase-13 MMP-13

Research Areas for MMP-13

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cellular Markers
Extracellular Matrix