Histone H2a Products

Description

Changes in chromatin structure play a large role in the regulation of transcription in eukaryotes (1). The nucleosome is the primary building block of chromatin, and is made up of four core histone proteins (H2A, H2B, H3 and H4) (2). It has been shown that DNA damage induces monoubiquitylation of histone H2A in the vicinity of DNA lesions. Ultraviolet -induced monoubiquitylation of H2A is dependent on functional nucleotide excision repair. It occurs after incision of the damaged strand and forms part of the cellular response to UV damage and suggests a role of this modification in DNA repair-induced chromatin remodeling (3).

Bioinformatics

Entrez	221613 Human 24828 Rat 8338 Human 92815 Human
Uniprot	NP_003508.1 Human P0C0S8 Human Q16777 Human Q96QV6 Human
Product By Gene ID	8338
Alternate Names	H2A histone family, member Q H2A/q H2AFQH2A H2A-GL101 histone 2, H2ac histone cluster 2, H2ac histone H2A type 2-C Histone H2A/q Histone H2A-GL101 histone IIa MGC74460

Research Areas for Histone H2a

Find related products by research area and learn more about each of the different research areas below.

Chromatin Research
Epigenetics
Histones and Modified Histones