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Hepatic Sinusoidal Endothelial Cells Antibody (SE-1) [FITC]

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Flow Cytometry: Hepatic Sinusoidal Endothelial Cells Antibody (SE-1) [FITC] [NB110-68095F] - Flow Cytometry: Surface staining of Rat Liver sinusoidal endothelial cells with Mouse anti-Rat Hepatic Sinusoidal Endothelial ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, Flow, ICC/IF, IHC
Clone
SE-1
Clonality
Monoclonal
Host
Mouse
Conjugate
FITC

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Hepatic Sinusoidal Endothelial Cells Antibody (SE-1) [FITC] Summary

Immunogen
Rat Hepatic Sinusoidal Endothelial Cells
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Reviewed Applications
Read 2 Reviews rated 4
using
NB110-68095F in the following applications:

Publications
Read Publication using
NB110-68095F in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Alternate Names for Hepatic Sinusoidal Endothelial Cells Antibody (SE-1) [FITC]

  • Hepatic cells
  • Hepatic Sinusoidal Endothelial Cells
  • HSE
  • SE1
  • Sinusoidal Endothelial Cells

Background

Hepatic sinusoidal endothelial cells (HSEC) plays a key role in various hepatic pathophysiological conditions and are known for their morphological uniqueness - numerous open fenestrations clustered in groups (sieve plates), lack of distinct basal lamina, and abundant vacuolar/vesicular structures. HSECs are distinct from vascular endothelial cells functionally/morphologically and besides providing sinusoidal barrier, they implicates in the balance or distribution of lipids, cholesterol, and vitamin A, and in the uptake of various substances via their specialized endocytotic mechanisms. SE-1 monoclonal antibody has been specifically designed to recognize an antigen expressed in HSEC, but not in other cell types including vascular endothelial cells. Experiments on developing liver have revealed that the expression of SE-1 antigen is possibly regulated via intimate association of HSECs with hepatocytes. Hepatic sinusoidal endothelial cells (SE-1) antibody has been extensively used as one of the most reliable markers for rat HSEC by Western blot and immunohistochemistry analysis and is a useful tool for studying the role of HSE in various hepato-pathophysiological conditions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Hepatic Sinusoidal Endothelial Cells Antibody (NB110-68095F)(1)

We have publications tested in 1 confirmed species: Rat.

We have publications tested in 1 application: FLOW.


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FLOW
(1)
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Rat
(1)
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Reviews for Hepatic Sinusoidal Endothelial Cells Antibody (NB110-68095F) (2) 42

Average Rating: 4
(Based on 2 reviews)
We have 2 reviews tested in 1 species: Rat.

Reviews using NB110-68095F:
Filter by Applications
Flow
(1)
IHC-Fr
(1)
All Applications
Filter by Species
Rat
(2)
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Images Ratings Applications Species Date Details
Flow Cytometry Hepatic Sinusoidal Endothelial Cells NB110-68095F
Enlarge
4
reviewed by:
Maria Martell
Flow Rat 02/28/2017
View

Summary

ApplicationFlow Cytometry
Sample TestedLiver sinusoidal endothelial cells
SpeciesRat
LotA-3-020817-F
Immunohistochemistry-Frozen Hepatic Sinusoidal Endothelial Cells NB110-68095F
Enlarge
4
reviewed by:
Maria Martell
IHC-Fr Rat 01/05/2017
View

Summary

ApplicationImmunohistochemistry-Frozen
Sample TestedFrozen Rat Liver Tissue sections
SpeciesRat
LotA-1

Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Hepatic Sinusoidal Endothelial Cells Antibody (NB110-68095F) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

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Recent Reviews

4
5
0
4
2
3
0
2
0
1
0

Maria Martell
02/28/2017
Application: Flow
Species: Rat

Maria Martell
01/05/2017
Application: IHC-Fr
Species: Rat