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Hereditary Spherocytosis: Disease Bioinformatics

Research of Hereditary Spherocytosis has been linked to Anemia, Anemia, Hemolytic, Hemolysis (disorder), Anemia, Hemolytic, Congenital, Thalassemia. The study of Hereditary Spherocytosis has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Hereditary Spherocytosis include Pathogenesis, Transport, Localization, Anion Transport, Aging. These pathways complement our catalog of research reagents for the study of Hereditary Spherocytosis including antibodies and ELISA kits against SPHEROCYTOSIS, RBC, HB, ITP, GLYCOPHORIN A.

Top Research Reagents

We have 2251 products for the study of Hereditary Spherocytosis that can be applied to Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

EPB42 Antibody (2G12)
H00002038-M01
Western Blot: EPB42 Antibody (2G12) [H00002038-M01] - Analysis of EPB42 expression in transfected 293T cell line by EPB42 monoclonal antibody (M01), clone 2G12.Lane 1: EPB42 transfected lysate(69.5 KDa).Lane 2: Non-transfected lysate.Immunocytochemistry/Immunofluorescence: EPB42 Antibody (2G12) [H00002038-M01] - Analysis of monoclonal antibody to EPB42 on HeLa cell . Antibody concentration 10 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

Glucose 6 Phosphate Dehydrogenase Antibody
NB100-236
Western Blot: Glucose 6 Phosphate Dehydrogenase Antibody [NB100-236] - Immunoblot analyses of protein expression for Nrf2 and antioxidant enzymes. Representative immunoblots of cytosolic extracts from the hearts of young and old mice under basal conditions and following EES. Protein blots were probed with anti-HO1, NQO1, GCLM, GCLC, Catalase, SOD1, SOD2, GSR, G6PD, GPX1 and GAPDH. Individual lanes indicate a single animal. Densitometry analysis of respective protein signals was performed using Image-J and expressed as relative intensity units calculated as mean values of young and old, *p<0.05. Individual lanes indicate each animal (n?=?6). #p<0.05-between basal and EES. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0045697), licensed under a CC-BY license.Western Blot: Glucose 6 Phosphate Dehydrogenase Antibody [NB100-236] - Detection of Human and Mouse G6PD by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, and mouse NIH3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-G6PD antibody NB100-236 used for WB at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, IB, IHC

19 Publications
Spectrin alpha 1 Antibody
NBP3-36712
Western Blot: Spectrin alpha 1 Antibody [NBP3-36712] - Western blot analysis of various lysates using Spectrin alpha 1 Rabbit pAb at 1:3000 dilution.<br/>Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 10s.Immunohistochemistry: Spectrin alpha 1 Antibody [NBP3-36712] - Immunohistochemistry analysis of paraffin-embedded Human tonsil using Spectrin alpha 1 Rabbit pAb at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ELISA, ICC/IF

EPB41 Antibody (3D9)
H00002035-M01
Western Blot: EPB41 Antibody (3D9) [H00002035-M01] - Analysis of EPB41 expression in transfected 293T cell line by EPB41 monoclonal antibody (M01), clone 3D9.Lane 1: EPB41 transfected lysate(81 KDa).Lane 2: Non-transfected lysate.Immunocytochemistry/Immunofluorescence: EPB41 Antibody (3D9) [H00002035-M01] - Analysis of monoclonal antibody to EPB41 on HeLa cell . Antibody concentration 10 ug/ml.

Mouse Monoclonal
Species Human
Applications WB, ELISA, ICC/IF

Ankyrin 1 Antibody
NBP1-71805
Western Blot: Ankyrin 1 Antibody [NBP1-71805] - Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 mcg) cells. Affinity purified rabbit anti-Ankyrin 1 antibody used for WB at 0.4 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 6 mcg/mg lysate. Ankyrin 1 was also immunoprecipitated by another rabbit anti-Ankyrin 1 antibody, which recognizes an upstream epitope.

Rabbit Polyclonal
Species Human
Applications WB, IP

     1 Review

2 Publications
MUC1 Antibody (SM3) - BSA Free
NB120-22711
Immunocytochemistry/Immunofluorescence: MUC-1 Antibody (SM3) [NB120-22711] - MCF7 cells were fixed for 10 minutes using 10% formalin and then permeabilized for 5 minutes using 1X PBS + 0.05% Triton-X100. The cells were incubated with anti-MUC1 [SM3] at 5 ug/ml overnight at 4C and detected with an anti-mouse IgG Dylight 488 (Green) at a 1:500 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective.Immunohistochemistry-Paraffin: MUC-1 Antibody (SM3) [NB120-22711] - IHC analysis of formalin fixed paraffin embedded tissue section of human breast cancer xenograft using MUC-1 antibody clone SM3 at 1:10 dilution. The xenograft section depicted a very specific and intense signal in the periphery of the cancer cells. The necrotic cells also developed a strong immune-positivity while the tumor stroma as well as the nuclei of cells were negative for immunostaining.

Mouse Monoclonal
Species Human, Mouse
Applications ELISA, Flow, ICC/IF

14 Publications
ETFA Antibody
NBP1-84854
Immunohistochemistry-Paraffin: ETFA Antibody [NBP1-84854] - Staining of human colon, kidney, liver and pancreas using Anti-ETFA antibody NBP1-84854 (A) shows similar protein distribution across tissues to independent antibody NBP1-84856 (B).Western Blot: ETFA Antibody [NBP1-84854] - Analysis in U2OS cells transfected with control siRNA, target specific siRNA probe #1 and #2, using anti-ETFA antibody. Remaining relative intensity is presented.

Rabbit Polyclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

NIK/MAP3K14 Antibody - BSA Free
NBP2-23603
Western Blot: NIK/MAP3K14 Antibody [NBP2-23603] - Detection of MAP3K14 in U2OS cell lysate.Immunocytochemistry/Immunofluorescence: NIK/MAP3K14 Antibody [NBP2-23603] - MAP3K14 antibody was tested in U2OS cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

1 Publication
EPB41L1 Antibody
NBP2-31572
Western Blot: EPB41L1 Antibody [NBP2-31572] - Analysis using Anti-EPB41L1 antibody NBP2-31572 (A) shows similar pattern to independent antibody NBP2-31650 (B).Immunocytochemistry/Immunofluorescence: EPB41L1 Antibody [NBP2-31572] - Immunofluorescent staining of human cell line A549 shows localization to plasma membrane.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

Haptoglobin [HRP]
DHAPG0
N/A Haptoglobin [HRP]N/A Haptoglobin [HRP]


Species Human
Applications ELISA

7 Publications
Erythropoietin/EPO [HRP]
MEP00B
N/A Erythropoietin/EPO [HRP]N/A Erythropoietin/EPO [HRP]


Species Mouse
Applications ELISA

105 Publications
Holo-Transferrin [Unconjugated]
2914-HT


Species Human
Applications BA

51 Publications
Band 3 Antibody
NBP2-49409
Immunohistochemistry-Paraffin: Band 3 Antibody [NBP2-49409] - Staining of human cerebral cortex shows low expression as expected.Immunohistochemistry: Band 3 Antibody [NBP2-49409] - Staining of human spleen shows strong positivity in erythrocytes.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-P

Acetylcholinesterase/ACHE Antibody
NB100-1519
Western Blot: Acetylcholinesterase/ACHE Antibody [NB100-1519] - Staining (0.3ug/ml) of Jurkat (A) and (0.5ug/ml) HepG2 (B) cell lysate (35ug protein in RIPA buffer). Detected by chemiluminescence.Immunocytochemistry/Immunofluorescence: Acetylcholinesterase/ACHE Antibody [NB100-1519] - Immunofluorescence analysis of paraformaldehyde fixed U2OS cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml), showing nuclear, membrane and cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml).

Goat Polyclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

     1 Review

1 Publication
Spectrin beta 1 Antibody (4C3)
NB300-574
Western Blot: Spectrin beta 1 Antibody (4C3) [NB300-574] - Analysis of 25 ug of Hela cell lysates.Immunocytochemistry/Immunofluorescence: Spectrin beta 1 Antibody (4C3) [NB300-574] - Analysis of Spectrin beta-1 (green) showing staining in the cytoplasm of A431 cells (right) compared to a negative control without primary antibody (left).

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

2 Publications

Related Genes

Hereditary Spherocytosis has been researched against:

Related Pathways

Hereditary Spherocytosis has been linked to:

Related Diseases

Hereditary Spherocytosis has been studied in relation to diseases such as:

Related PTMs

Hereditary Spherocytosis has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Hereditary Spherocytosis is also known as hereditary spherocytosis, congenital spherocytic hemolytic anemia, hereditary spherocytosis (disorder), minkowski chauffard syndrome, spherocytosis hereditary, spherocytosis, type 1, anemia spherocytic, hartnup disease, spherocytosis, h disease, anemia, hs.