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Chronic Secretory Otitis Media: Disease Bioinformatics

Research of Chronic Secretory Otitis Media has been linked to Otitis Media With Effusion, Otitis Media, Ear Inflammation, Otitis Media Chronic, Otitis Media Acute. The study of Chronic Secretory Otitis Media has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Chronic Secretory Otitis Media include Pathogenesis, Secretion, Immune Response, Complement Activation, Inflammatory Response. These pathways complement our catalog of research reagents for the study of Chronic Secretory Otitis Media including antibodies and ELISA kits against MUCIN, C3, COL2A1, ELANE, HP.

Top Research Reagents

We have 5039 products for the study of Chronic Secretory Otitis Media that can be applied to Chromatin Immunoprecipitation (ChIP), Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

NOD2 Antibody (2D9) - BSA Free
NB100-524
Western Blot: NOD2 Antibody (2D9) [NB100-524] - HCMV infection induces NOD2 mRNA and protein in HFFs and U373 cells. E. U373 glioma cells were infected with HCMV Towne strain and levels of NOD1, NOD2 and GAPDH mRNAs were measured by qRT-PCR at indicated time points. F. HFFs were infected with HCMV (Towne) at MOI of 1 PFU/cell and levels of NOD2 protein and B-actin were determined 48 and 72 hpi. G. HFFs were infected with HCMV (Towne) strain at MOI of 0.03 or 3 PFU/cell and levels of NOD2 protein and B-actin were determined at 48 hpi. Quantitative data represent mean values (+/-SD) of triplicate determinations from three independent experiments (*p<0.05, **p<0.01, ***p<0.001, one-way ANOVA test). Image collected and cropped by CiteAb from the following publication (//doi.org/10.1371/journal.pone.0092704.g001) licensed under a CC-BY license.Immunohistochemistry-Frozen: NOD2 Antibody (2D9) [NB100-524] - Overlay of NOD2-DyLight 488 (green) with phase contrast of murine colon. Image from verified customer review.

Mouse Monoclonal
Species Human, Mouse
Applications WB, Flow, ICC/IF

     1 Review

26 Publications
Collagen II Antibody (5B2.5) - BSA Free
NB600-844
Western Blot: Collagen II Antibody (5B2.5) [NB600-844] - Expression levels of related genes during differentiation induction in the 2D environment. Expression of ACAN, collagen II, collagen X and Runx2 was detected by western blotting on day 10 during induction. Image collected and cropped by Citeab from the following publication (Chondrogenic differentiation of bone marrow-derived mesenchymal stem cells following transfection with Indian hedgehog and sonic hedgehog using a rotary cell culture system. Cell Mol Biol Lett (2019)) licensed under a CC-BY license.Immunohistochemistry-Paraffin: Collagen II Antibody (5B2.5) [NB600-844] - Staining results for the process of differentiation induction in the RCCS environment. Collagen II immune-histochemical staining on cells after inoculation onto slides. Image collected and cropped by Citeab from the following publication (Chondrogenic differentiation of bone marrow-derived mesenchymal stem cells following transfection with Indian hedgehog and sonic hedgehog using a rotary cell culture system. Cell Mol Biol Lett (2019)) licensed under a CC-BY license.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, ICC/IF, IHC

50 Publications
AP3B1 Antibody
NBP1-89228
Immunocytochemistry/Immunofluorescence: AP3B1 Antibody [NBP1-89228] - Staining of human cell line U-2 OS shows localization to nucleoplasm.Immunohistochemistry-Paraffin: AP3B1 Antibody [NBP1-89228] - Staining of human rectum shows cytoplasmic positivity in glandular cells.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

MUC5AC Antibody (45M1)
NBP2-15196
Immunohistochemistry: MUC5AC Antibody (45M1) [NBP2-15196] - Representative micrographs and high magnification insets illustrating the airway cell population of terminal bronchioles from conditional Nedd4-2-/- mice and littermate controls after 3 months of doxycycline induction with anti-Muc5ac and anti-CCSP antibodies (n = 4/group). Scale bars, 60 and 15 um (insets). Image collected and cropped by CiteAb from the following publication https://www.nature.com/articles/s41467-020-15743-6) licensed under a CC-BY license.Immunohistochemistry-Paraffin: MUC5AC Antibody (45M1) [NBP2-15196] - Analysis using the Azide and BSA Free version of NBP2-15196. Detection Human stomach.

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, DB, Flow

     5 Reviews

28 Publications
RNASE3 Antibody
NBP2-33778
Immunohistochemistry-Paraffin: RNASE3 Antibody [NBP2-33778] - Analysis in human bone marrow and skeletal muscle tissues using NBP2-33778 antibody. Corresponding RNASE3 RNA-seq data are presented for the same tissues.Western Blot: RNASE3 Antibody [NBP2-33778] - Analysis in human cell line U-937 MG.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

1 Publication
Prolyl Oligopeptidase/PREP Antibody
NBP2-33950
Immunocytochemistry/Immunofluorescence: Prolyl Oligopeptidase/PREP Antibody [NBP2-33950] - Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol. Antibody stainin is shown in green. Immunohistochemistry-Paraffin: Prolyl Oligopeptidase/PREP Antibody [NBP2-33950] - Staining of human pancreas shows low expression as expected.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

3 Publications
Myeloperoxidase/MPO Antibody [Unconjugated]
AF3667
Western blot shows lysates of HL-60 human acute promyelocytic leukemia cell line, human neutrophil cells, and mouse spleen tissue. PVDF membrane was probed with 0.5 µg/mL of Goat Anti-Human/Mouse Myeloperoxidase/MPO Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3667) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (<a class=Myeloperoxidase/MPO was detected in immersion fixed mouse splenocytes using Goat Anti-Human/Mouse Myeloperoxidase/MPO Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3667) at 15 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; <a class=

Goat Polyclonal
Species Human, Mouse
Applications WB, Simple Western, IHC

     3 Reviews

167 Publications
Complement Component C3d Antibody [Unconjugated]
AF2655
Complement Component C3d was detected in perfusion fixed frozen sections of mouse kidney using Goat Anti-Mouse Complement Component C3d Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2655) overnight at 4 °C. Tissue was stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # <A class=NoLineLink href= Complement Component C3d was detected in perfusion fixed paraffin-embedded sections of rat kidney using Goat Anti-Mouse Complement Component C3d Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2655) at 3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (Catalog # <a class=

Goat Polyclonal
Species Mouse, Rat
Applications WB, IHC

58 Publications
Haptoglobin [HRP]
DHAPG0
N/A Haptoglobin [HRP]N/A Haptoglobin [HRP]


Species Human
Applications ELISA

7 Publications
TNF-alpha [Unconjugated]
210-TA
Recombinant Human TNF-alpha (Catalog # 210-TA) has a molecular weight (MW) of 53.1 kDa as analyzed by SEC-MALS, suggesting that this protein is a homotrimer.  MW may differ from predicted MW due to post-translational modifications (PTMs) present (i.e. Glycosylation).Recombinant Human TNF-alpha (Catalog # 210‑TA) induces cytotoxicity in the L-929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. The ED<sub>50</sub> for this effect is 25‑100 pg/mL.


Species Human
Applications BA

     3 Reviews

811 Publications
IL-2 [Unconjugated]
202-IL
As an alternative, please consider our next generation Recombinant Human IL-2 (<a class=


Species Human
Applications BA

     4 Reviews

377 Publications
IL-1 beta/IL-1F2 [Unconjugated]
201-LB
Recombinant Human IL-1beta Protein (Catalog # 201-LB) has a molecular weight (MW) of 17.0 kDa as analyzed by SEC-MALS, suggesting that this protein is a monomer.Recombinant Human IL-1 beta /IL-1F2 (Catalog # 201-LB) stimulates cell proliferation of the D10.G4.1 mouse helper T cell line. The ED<sub>50</sub> for this effect is <12 pg/mL.


Species Human
Applications BA

594 Publications
CXCL8/IL-8 [Biotin]
DY208
N/A CXCL8/IL-8 [Biotin]


Species Human
Applications ELISA

463 Publications
IL-13 [Biotin]
DY413
N/A IL-13 [Biotin]


Species Mouse
Applications ELISA

148 Publications
DLC1 Antibody - Isoform 1 and 3
NB300-917
Immunohistochemistry-Paraffin: DLC1 Antibody - Isoform 1 and 3 [NB300-917] - Negative Control showing staining of paraffin embedded Mouse Adrenal Gland, with no primary antibody.Immunohistochemistry-Paraffin: DLC1 Antibody - Isoform 1 and 3 [NB300-917] - Staining of paraffin embedded Mouse Adrenal Gland. Antibody at 4 ug/mL. Heat induced antigen retrieval with citrate buffer pH 6, HRP-staining.

Goat Polyclonal
Species Human, Mouse
Applications ICC/IF, IHC, IHC-P

2 Publications
GRHL3 Antibody
NBP2-57087
Immunohistochemistry-Paraffin: GRHL3 Antibody [NBP2-57087] - Analysis in human urinary bladder and skeletal muscle tissues. Corresponding GRHL3 RNA-seq data are presented for the same tissues.Immunocytochemistry/Immunofluorescence: GRHL3 Antibody [NBP2-57087] - Staining of human cell line MCF7 shows localization to nucleoplasm.

Rabbit Polyclonal
Species Human
Applications ICC/IF, IHC, IHC-P

Lysozyme Antibody - BSA Free
NBP2-61118
Immunocytochemistry/Immunofluorescence: Lysozyme Antibody [NBP2-61118] - NIH3T3 cells were fixed and permeabilized for 10 minutes using -20C MeOH. The cells were incubated with anti-Lysozyme NBP2-61118 at 2 ug/ml overnight at 4C and detected with an anti-rabbit Dylight 488 (Green) at a 1:1000 dilution for 60 minutes. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 100X objective and digitally deconvolved.Western Blot: Lysozyme Antibody [NBP2-61118] - Total protein from human cell lines THP-1 and HepG2, human stomach and kidney as well as mouse kidney was separated on a 4-20% gel by SDS-PAGE, transferred to 0.2 um PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 2.0 ug/ml anti-Lysozyme in 5% non-fat milk in TBST and detected with an anti-rabbit HRP secondary antibody using chemiluminescence.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, Simple Western, Flow

7 Publications
Neutrophil Elastase/ELA2 [Biotin]
DY9167-05
N/A Neutrophil Elastase/ELA2 [Biotin]


Species Human
Applications ELISA

21 Publications
MMP-12 Antibody (SR03-23)
NBP2-67344
Western Blot: MMP-12 Antibody (SR03-23) [NBP2-67344] - Analysis of MMP-12 on different lysates with Rabbit anti-MMP-12 antibody at 1/500 dilution. Lane 1: Mouse lung tissue lysate Lane 2: Rat lung tissue lysate Lysates/proteins at 20 ug/Lane. Predicted band size: 54 kDa Observed band size: 40 kDa Exposure time: 1 minute; 8% SDS-PAGE gel. Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody at 1/500 dilution was used in 5% NFDM/TBST at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody at 1:200,000 dilution was used for 1 hour at room temperature.Immunohistochemistry-Paraffin: MMP-12 Antibody (SR03-23) [NBP2-67344] - Analysis of paraffin-embedded mouse lung tissue using anti-MMP12 antibody. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4) for 20 minutes.The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (1/50) for 30 minutes at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, Flow, ICC/IF

9 Publications

Related Genes

Chronic Secretory Otitis Media has been researched against:

Related Pathways

Chronic Secretory Otitis Media has been linked to:

Related Diseases

Chronic Secretory Otitis Media has been studied in relation to diseases such as:

Related PTMs

Chronic Secretory Otitis Media has been studied in relation to posttranslational modifications (PTMs) including:

Alternate Names

Chronic Secretory Otitis Media is also known as Chronic Middle Ear Effusion, Chronic Otitis Media With Effusion.