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Branchio-oto-renal Syndrome: Disease Bioinformatics

Research of Branchio-oto-renal Syndrome has been linked to Complete Hearing Loss, Branchiooculofacial Syndrome, Branchioma, Dysplasia, Pathologic Fistula. The study of Branchio-oto-renal Syndrome has been mentioned in research publications which can be found using our bioinformatics tool below. Researched pathways related to Branchio-oto-renal Syndrome include Localization, Pathogenesis, Ear Development, Inner Ear Development, Transport. These pathways complement our catalog of research reagents for the study of Branchio-oto-renal Syndrome including antibodies and ELISA kits against EYA1, CDCA8, SIX1, TFAP2A, LACRIMAL.

Top Research Reagents

We have 687 products for the study of Branchio-oto-renal Syndrome that can be applied to Chromatin Immunoprecipitation, Chromatin Immunoprecipitation (ChIP), Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot from our catalog of antibodies and ELISA kits.

EYA3 Antibody
NBP1-46818
Western Blot: EYA3 Antibody [NBP1-46818] - Samples: Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 ug) cells. Antibodies: Affinity purified rabbit anti-EYA3 antibody NBP1-46818 used for WB at 0.04 ug/ml (A) and 0.4 ug/ml (B) and used for IP at 3 ug/mg lysate. EYA3 was also immunoprecipitated by rabbit anti-EYA3 antibody NBP1-46819, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure times of 30 seconds (A) and 10 seconds (B).Immunohistochemistry: EYA3 Antibody [NBP1-46818] - Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-EYA3 used at a dilution of 1:200 (1ug/ml). Detection: DAB

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

EYA2 Antibody
NBP1-84026
Western Blot: EYA2 Antibody [NBP1-84026] - Analysis in human cell line SCLC-21H.Immunohistochemistry-Paraffin: EYA2 Antibody [NBP1-84026] - Staining of human testis shows moderate to strong nuclear positivity in cells in seminiferous ducts.

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

2 Publications
SIX1 Antibody
NBP1-84264
Immunohistochemistry-Paraffin: SIX1 Antibody [NBP1-84264] - Staining in human skeletal muscle and liver tissues . Corresponding SIX1 RNA-seq data are presented for the same tissues.Western Blot: SIX1 Antibody [NBP1-84264] - Analysis in Rh30 cells transfected with control siRNA, target specific siRNA probe #1 and #2. Remaining relative intensity is presented. Loading control: Anti-PPIB.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ChIP, ICC/IF

18 Publications
SIX5 Antibody
NBP1-85009
Immunohistochemistry-Paraffin: SIX5 Antibody [NBP1-85009] - Moderately differentiated mouse adenocarcinomas show moderate nuclear Six5 expression. IHC-P image submitted by a verified customer review.Immunohistochemistry-Paraffin: Six5 Antibody [NBP1-85009] - Staining of human liver shows strong cytoplasmic positivity in hepatocytes.

Rabbit Polyclonal
Species Human, Mouse
Applications IHC, IHC-P

     1 Review

SLC26A4 Antibody
NBP1-85237
Immunohistochemistry-Paraffin: SLC26A4 Antibody [NBP1-85237] - Staining of human lymph node shows no positivity in non-germinal center cells as expected.Immunohistochemistry-Paraffin: SLC26A4 Antibody [NBP1-85237] - Staining of human thyroid gland shows weak to moderate cytoplasmic and membranous positivity in follicle cells.

Rabbit Polyclonal
Species Human
Applications IHC, IHC-Fr, IHC-P

     1 Review

2 Publications
TCF-2/HNF-1 beta Antibody
NBP1-89680
Immunohistochemistry-Paraffin: TCF-2/HNF-1 beta Antibody [NBP1-89680] - Analysis in human kidney and lymph node tissues. Corresponding HNF1B RNA-seq data are presented for the same tissues.Western Blot: TCF-2/HNF-1 beta Antibody [NBP1-89680] - Analysis in human kidney tissue.

Rabbit Polyclonal
Species Human, Mouse
Applications WB, Simple Western, ICC/IF

     1 Review

7 Publications
Borealin Antibody
NBP1-89951
Western Blot: Borealin Antibody [NBP1-89951] - Aurora B preferentially binds to H3R2me2a and recruits CPC components. Lysates of TN-arrested Aurora B-depleted cells were supplemented with recombinant Survivin and Borealin proteins with or without recombinant Aurora B protein. The lysates were incubated with antibodies against INCENP and the H3R2me2a peptide, and pulldown was conducted with agarose A beads. The binding was visualized by immunoblotting. The asterisk denotes the light chain of antibodies. Image collected and cropped by CiteAb from the following publication (https://www.nature.com/articles/s41467-020-14511-w), licensed under a CC-BY license.Immunocytochemistry/Immunofluorescence: Borealin Antibody [NBP1-89951] - Staining of human cell line U-251 MG shows localization to nucleus & nucleoli. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF, IHC

4 Publications
SHARPIN Antibody
NBP2-04116
Immunoprecipitation: SHARPIN Antibody [NBP2-04116] - Samples: Whole cell lysate from HeLa (15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 ug) and Jurkat (J; 50 ug) cells. Antibodies: Affinity purified rabbit anti-SHARPIN antibody NBP2-04116 used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 6 ug/mg lysate. SHARPIN was also immunoprecipitated by rabbit anti-SHARPIN antibody, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B).

Rabbit Polyclonal
Species Human, Mouse
Applications WB, ICC/IF, IHC

4 Publications
DACH1 Antibody
NBP2-27192
Western Blot: DACH1 Antibody [NBP2-27192] - Analysis of DACH1 in human placenta lysate using NBP2-27192 at 5 ug/ml.Immunohistochemistry-Paraffin: DACH1 Antibody [NBP2-27192] - Analysis of Dach1 in formalin-fixed, paraffin-embedded human kidney tissue using an isotype control (top left) and this antibody (bottom left, right) at 5 ug/ml.

Rabbit Polyclonal
Species Human, Mouse, Bovine
Applications WB, IHC, IHC-P

NeuroD1 Antibody [Unconjugated]
AF2746
Neurogenic Differentiation factor 1 (NeuroD1) was detected in immersion fixed beta TC-6 mouse beta cell insulinoma cell line using Human/Mouse NeuroD1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2746) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # <a class=

Goat Polyclonal
Species Human, Mouse
Applications WB, ICC

18 Publications
SALL1 Antibody (K9814) [Unconjugated]
PP-K9814-00
Stepwise differentiation of human iPSCs towards renal progenitor cells (RPCs).(a) Schematic description of the two-stage protocol applied to iPSC-renal commitment. (b, c, d, e) Immunofluorescence of iPSCs (derived from retroviral transfected dermal fibroblasts) exposed to differentiating media. (b) The pluripotency markers SSEA4, TRA-1-81, Nanog, ME marker T(Bry) and IM marker Osr1. (c) IM and MM marker expression as Wt1, Pax8, Pax2, Six2 and Sall1. (d) Renal progenitor markers CD133, CD24, NCAM, glomerular epithelial marker Claudin1 and proximal tubular epithelial markers AQP1, GGT1. (e) Markers identifying endodermal AFP, ectodermal Pax6, and cardiac mesodermal Nkx2.5 derivation. Nuclei are stained with DAPI (blue). Scale bars: 20 μm (b, c, d, e). Image collected and cropped by CiteAb from the following publication (https://www.nature.com/articles/srep08826), licensed under a CC-BY license. Not internally tested by R&D Systems.

Mouse Monoclonal
Species Human
Applications WB, IHC, IP

10 Publications
Connexin 26/GJB2 Antibody - BSA Free
NBP2-41304
Western Blot: Connexin 26/GJB2 Antibody [NBP2-41304] - Western blotting analysis detects Cx26 using R(alpha)Cx26-Ct or R(alpha)Cx26-cl antibodies. (a) R(alpha)Cx26-Ct (A) and R(alpha)Cx26-cl (B) antibodies detected a specific 26kDa band on pig heart tissue lysates (lanes A and B are cropped blots obtained from the same gel). R(alpha)Cx26-cl recognized the 26kDa band on human and rat heart (H) lysates and on rat liver (L) sample (positive control) although two unspecific bands at molecular weights lower than 26kDa were detected. No bands were detected on smooth muscle (SM) tissue lysates (negative control) by R(alpha)Cx26-cl. R(alpha)GAPDH was used as protein loading control for rat tissue samples run on the same gel. Image collected and cropped by CiteAb from the following publication (nature.com/articles/s41598-018-32405-2), licensed under a CC-BY license.Immunocytochemistry/Immunofluorescence: Connexin 26/GJB2 Antibody [NBP2-41304] - Cx26 distribution at level of the cardiomyocyte cytoplasm. Confocal laser scanning microscopy: representative images of rat and pig heart sections. Double immunofluorescence analysis for Cx26 (red) and Cx43 (green) show a distinct cell localization of the two Cxs. (a) Three dimensional picture of the maximum intensity projection of the raw images of longitudinal rat heart section treated with R(alpha)Cx26-cl and M(alpha)Cx43. Scale bar: 20um. Image collected and cropped by CiteAb from the following publication (nature.com/articles/s41598-018-32405-2), licensed under a CC-BY license.

Rabbit Polyclonal
Species Human, Rat, Porcine
Applications WB, ELISA, ICC/IF

5 Publications
BMP-4 [Unconjugated]
314-BP
Recombinant Human BMP‑4 (Catalog # 314-BP) induces BMP responsive SEAP reporter activity in HEK293 human embryonic kidney cells. The ED<sub>50</sub> for this effect is 0.70-7.00 ng/mL.1 ug/lane of Recombinant Human BMP-4 was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by silver staining, showing major bands at 22-25 kDa and 37-41 kDa, respectively. Multiple bands in gel are due to variable glycosylation.<p style=


Species Human
Applications BA, BA

504 Publications
TBX1 Antibody (OTI1C2)
NBP2-46076
Western Blot: TBX1 Antibody (OTI1C2) [NBP2-46076] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TBX1.Immunohistochemistry-Paraffin: TBX1 Antibody (OTI1C2) [NBP2-46076] - Analysis of Human lymph node tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)

Mouse Monoclonal
Species Human, Mouse, Rat
Applications WB, IHC, IHC-P

1 Publication
BRN4 Antibody
NBP2-68787
Western Blot: BRN4 Antibody [NBP2-68787] - Analysis in human cerebral cortex tissue.Immunocytochemistry/Immunofluorescence: BRN4 Antibody [NBP2-68787] - Staining of human cell line AF22 shows localization to nucleus. Antibody staining is shown in green.

Rabbit Polyclonal
Species Human
Applications WB, ICC/IF

Myoglobin Antibody (2269B) [Unconjugated]
MAB97203
Western blot shows lysates of human heart tissue, mouse heart tissue, rat heart tissue, and human liver tissue. PVDF membrane was probed with 0.5 µg/mL of Rabbit Anti-Human Myoglobin Monoclonal Antibody (Catalog # MAB97203) followed by HRP-conjugated Anti-Rabbit IgG Secondary Antibody (Catalog # <a class= Myoglobin was detected in immersion fixed paraffin-embedded sections of human heart using Rabbit Anti-Human Myoglobin Monoclonal Antibody (Catalog # MAB97203) at 3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Rabbit IgG VisUCyte™ HRP Polymer Antibody (Catalog # <a class=

Rabbit Monoclonal
Species Human, Mouse, Rat
Applications WB, Simple Western, ELISA

EYA1 Antibody
NBP2-87382
Western Blot: EYA1 Antibody [NBP2-87382] - Host: Rabbit. Target Name: EYA1. Sample Tissue: Human THP-1 Whole Cell. Antibody Dilution: 1ug/mlImmunohistochemistry: EYA1 Antibody [NBP2-87382] - Immunohistochemistry with Human kidney lysate tissue at an antibody concentration of 5.0ug/ml using anti-EYA1 antibody

Rabbit Polyclonal
Species Human
Applications WB, IHC, IHC-P

AP2 alpha Antibody (3B5)
NB100-74359
Western Blot: AP2 alpha Antibody (3B5) [NB100-74359] - Analysis was performed on whole cell extracts (30 ug lysate) of PC-3 (Lane1), A-431 (Lane2), Mouse Placenta (Lane3) and RAW 264.7 (Lane5). Immunocytochemistry/Immunofluorescence: AP2 alpha Antibody (3B5) [NB100-74359] - Analysis of AP2 using Anti-AP2 Monoclonal Antibody (3B5) shows staining in Hela Cells. AP2 staining (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with or an antibody recognizing AP2 at a dilution of 1:100 over night at 4C, washed with PBS and incubated with a DyLight-488 conjugated secondary antibody. Images were taken at 60X magnification.

Mouse Monoclonal
Species Human, Mouse, Chicken
Applications WB, ICC/IF, IHC

     1 Review

3 Publications