Species: Mu
Applications: IHC
Host: Rat Monoclonal
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC
Host: Rabbit Monoclonal
Species: Hu
Applications: WB, Simple Western, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: Bioactivity
Species: Bv
Applications: Bioactivity
Description
Vitronectin also called serum spreading factor or complement S-protein, is a member of the pexin family (1). Found in serum and in tissues, Vitronectin exist in two forms; as a single chain (75kDa) and as a clipped form composed of two chains (65kDa and 10kDa). Vitronectin promotes cell adhesion, spreading and migration through specific interactions with cellular integrins, and inhibits cytolysis by the complement C5b-9 complex (2-4). Vitronectin also interacts with several critical proteins that regulate thrombosis and fibrinolysis. Vitronectin is phosphorylated by PKA and CKII (5).
Bioinformatics
| Entrez |
Mouse
Rat
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
7448 |
| Alternate Names |
- complement S-protein
- epibolin
- serum spreading factor
- Serum-spreading factor
- somatomedin B
- S-protein
- V75
- vitronectin (serum spreading factor, somatomedin B, complement S-protein)
- vitronectin
- VN
- VNT
|
Research Areas for Vitronectin
Find related products by research area and learn more about each of the different research areas below.
ImmunologyInnate Immunity
![Immunohistochemistry Vitronectin Antibody (347317) [Unconjugated]](http://images.novusbio.com/fullsize2/Vitronectin_MAB38751_Immunohistochemistry_7011.jpg)
![Western Blot Vitronectin Antibody (342603) [Unconjugated]](http://images.novusbio.com/fullsize2/Vitronectin_MAB2349_Western_Blot_20043.jpg)
![Sandwich ELISA Vitronectin Antibody Pair [HRP]](http://images.novusbio.com/fullsize/Vitronectin-Antibody-Pair-[HRP]-Sandwich-ELISA-NBP2-79457-img0001.jpg)
![Immunohistochemistry Vitronectin Antibody (342603) [Unconjugated]](http://images.novusbio.com/fullsize2/Vitronectin_MAB2349_Immunohistochemistry_7361.jpg)
![Simple Western Vitronectin Antibody (342603) [Unconjugated]](http://images.novusbio.com/fullsize2/16254.jpg)
