VCAM-1/CD106 Products

Description

CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 ( alpha4/ beta1 integrin) and LPAM-1 ( alpha4/ beta7 integrin). The 429 antibody has been reported to partially block VCAM-1-mediated binding.

Bioinformatics

Entrez	22329 Mouse 25361 Rat 7412 Human
Uniprot	AAH17276 Human CAA47989 Mouse NP_001069 Human NP_001069.1 Human NP_542413 Human P19320 Human P29533 Mouse X53051 Human
Product By Gene ID	7412
Alternate Names	CD106 antigen CD106 DKFZp779G2333 INCAM-100 L1CAM MGC99561 vascular cell adhesion molecule 1 vascular cell adhesion protein 1 V-CAM 1 VCAM1 VCAM-1

Research Areas for VCAM-1/CD106

Find related products by research area and learn more about each of the different research areas below.

Cancer
Mesenchymal Stem Cell Markers
Phospho-Specific
Stem Cell Markers