Species: Hu
Applications: WB, IHC, IP, ELISA
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
TR4 (TAK1, NR2C2) is an orphan nuclear receptor. TR4 was originally cloned from lymphoblastoma Raji cells or mouse brain cDNA library. No ligand has been reported. Northern blot shows TR4 is transcribed as a 9kb mRNA in many tissues and as a 2.8kb mRNA in testis, mainly in spermatocytes. TR4 has two isoforms called TR4alpha1 and TR4 alpha2,which differ in 19 amino acids coded by two separate exons. Both products translated from the 9kb transcript are ubiquitously expressed. Since TR4 binds to the same elements for the RAR-RXR or TR-RXR heterodimers, TR4 may have an inhibitory effect for retinoic-acid mediated transactivation.
Bioinformatics
| Uniprot |
Human
Human
Human
Mouse
|
| Product By Gene ID |
7182 |
| Alternate Names |
- hTAK1
- Nuclear hormone receptor TR4
- nuclear receptor subfamily 2 group C member 2
- nuclear receptor subfamily 2, group C, member 2
- Orphan nuclear receptor TAK1
- Orphan nuclear receptor TR4
- TAK1TR4TR2R1
- Testicular receptor 4
- TR4 nuclear hormone receptor
|
Research Areas for TR4/NR2C2
Find related products by research area and learn more about each of the different research areas below.
Neuroscience
![Immunocytochemistry/ Immunofluorescence TR4/NR2C2 Antibody (H0107B) [Unconjugated]](http://images.novusbio.com/fullsize/pp-h0107b-00_human-tr4-nr2c2-mab-clone-h0107b-41202412514818.jpg)
![Western Blot TR4/NR2C2 Antibody (H0107B) [Unconjugated]](http://images.novusbio.com/fullsize/pp-h0107b-00_human-tr4-nr2c2-mab-clone-h0107b-41202412511338.jpg)
