SUCLA2 Products

Description

Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6. (provided by RefSeq)

Bioinformatics

Entrez	8803 Human
Uniprot	AAH27587 Human NM_003850 Human
Product By Gene ID	8803
Alternate Names	A-BETA ATP-specific succinyl-CoA synthetase subunit beta beta subunit EC 6.2.1 EC 6.2.1.5 mitochondrial succinyl-CoA ligase [ADP-forming] subunit beta MTDPS5 Renal carcinoma antigen NY-REN-39 succinate-CoA ligase, ADP-forming, beta subunit succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial

Research Areas for SUCLA2

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Stem Cell Markers