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Description

Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.

Bioinformatics

Entrez	20692 Mouse 6678 Human
Uniprot	AAH04974 Human AAH04974.1 Human NM_003118 Human NP_003109.1 Human P07214 Mouse P09486 Human
Product By Gene ID	6678
Alternate Names	Basement-membrane protein 40 BM-40 ONcysteine-rich protein Osteonectin osteonectin Secreted protein acidic and rich in cysteine secreted protein, acidic, cysteine-rich (osteonectin)

Research Areas for SPARC

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Cycle and Replication

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