Species: Hu
Applications: WB, ELISA, Flow, ICC/IF, IHC, IP, MA
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ICC/IF, IHC, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF, IP, MA
Host: Mouse Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Description
Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF is a cardiac-enriched transcription factor that is required for the appearance of beating sarcomeres in the heart. In addition, SRF may also direct the expression of microRNAs that inhibit the expression of cardiac regulatory factors. SRF binding sites are also constitutive promotor elements in many muscle specific promoters. At the c-Fos SRE, formation of a ternary complex containing SRF and its accessory protein p62TCF appears to be important for signal transduction. Two related Ets domain proteins, Elk 1 and SRF accessory protein 1 (SAP 1) have DNA binding properties identical to that of p62TCF
Bioinformatics
Entrez |
Mouse Rat Human |
Uniprot |
Human Human Human Human |
Product By Gene ID |
6722 |
Alternate Names |
- MCM1
- serum response factor (c-fos serum response element-binding transcriptionfactor)
- serum response factor
|
Research Areas for Serum Response Factor SRF
Find related products by research area and learn more about each of the different research areas below.
Phospho-Specific